Tsukioka Takuma, Yamamoto Rhoji, Takahama Makoto, Nakajima Ryu, Tada Hirohito
Department of General Thoracic Surgery, Osaka City General Hospital, 2-13-22 Miyakojima Hondori, Miyakojima-ku, Osaka 534-0021, Japan.
Gen Thorac Cardiovasc Surg. 2012 Sep;60(9):618-20. doi: 10.1007/s11748-012-0065-8. Epub 2012 Jun 13.
A 48-year-old man with fever and dry cough was admitted to our hospital. Imaging examinations revealed a mass lesion with calcification in the right B(3)b bronchus and atelectasis in the distal lung area. Subsequently, right S(3) segmentectomy was performed. There was a hard polypoid mass completely obstructing the right B(3)b bronchus. Histopathological findings suggested a metaplastic bone formation with mature bone marrow tissue leading to the primary bronchial cartilage. A case of ectopic bone formation in subsegmental bronchus has never been reported thus far. The resident fibroblasts might transform into osteoblasts under appropriate environmental conditions and induce bone formation.
一名48岁发热伴干咳的男性患者入住我院。影像学检查显示右B(3)b支气管有一个伴有钙化的肿块病变，远端肺区有肺不张。随后，进行了右S(3)段切除术。发现一个坚硬的息肉样肿块完全阻塞了右B(3)b支气管。组织病理学检查结果提示化生骨形成，伴有成熟骨髓组织，通向原发性支气管软骨。到目前为止，尚未有亚段支气管异位骨形成的病例报道。驻留的成纤维细胞可能在适当的环境条件下转化为成骨细胞并诱导骨形成。
