Weninger Wolfgang J, Geyer Stefan H
Integrative Morphology Group, Center for Anatomy and Cell Biology, Medical University of Vienna, Austria.
Birth Defects Res C Embryo Today. 2012 Jun;96(2):163-75. doi: 10.1002/bdrc.21009.
Several types of "models" are used in modern biological and biomedical research and teaching. This article attempts to provide a brief explanation of the termini model organism, theoretic and mathematic model, three-dimensional (3D) model, and 4D model, and an overview about the generation and the fields of applications of these types of models. It will then focus on the application of theoretic and mathematic models, 3D models, 4D models, and simulation for researching cardiovascular morphogenesis.
现代生物学和生物医学研究及教学中使用了几种类型的“模型”。本文试图简要解释术语“模式生物”“理论和数学模型”“三维(3D)模型”及“四维(4D)模型”,并概述这些类型模型的产生及应用领域。然后将重点介绍理论和数学模型、3D模型、4D模型以及模拟在心血管形态发生研究中的应用。