Riviere J, Manciet G, Roger P, Guerin J, Barraud A M, Mauriac L, Kern A M, Rashedi M
Nouv Presse Med. 1979 Jun 16;8(27):2255-9.
In three patients suffering from Cushing's disease, exploration revealed an enclosed pituitary adenoma in one case and a microadenoma in two cases. Selective excision via a transphenoidal approach resulted in cure of Cushing's disease as reflected by complete regression of clinical signs and the restoration of circadian rythm of cortisol. Regular follow-up over a period of more than two years showed the persistence of normal regulation of the corticotrophic sector of the pituitary.
在3例库欣病患者中,探查发现1例为包裹性垂体腺瘤,2例为微腺瘤。经蝶窦入路选择性切除术后,临床症状完全消退,皮质醇昼夜节律恢复,库欣病得以治愈。超过两年的定期随访显示垂体促肾上腺皮质激素部分的调节功能持续正常。