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与使用合成代谢类固醇相关的脑血管意外的延迟诊断。

Delayed diagnosis of a cerebrovascular accident associated with anabolic steroid use.

作者信息

Cooper Isabelle, Reeve Nina, Doherty Warren

机构信息

Department of Anaesthetics, Cheltenham General Hospital, Cheltenham, UK.

出版信息

BMJ Case Rep. 2011 Jun 29;2011:bcr0220113857. doi: 10.1136/bcr.02.2011.3857.

Abstract

The authors report a case of atherosclerotic stroke in a 46-year-old recreational bodybuilder with a 20 year history of anabolic-adrenergic steroid (AAS) abuse. Cerebrovascular accident (CVA) occurred during his third week of hospital admission for an acute abdomen and on day 8, postemergency laparotomy. CVA presented with collapse, generalised seizures, reduced Glasgow Coma Score and severe hypertension. He was subsequently admitted to the intensive care unit (ICU), where initial investigations did not illustrate an underlying diagnosis. By day 4 in ICU, there had been no significant clinical improvement and radiological investigations were repeated, identifying a left frontal lobe infarct in the middle cerebral artery territory. The authors propose CVA was secondary to AAS. After a prolonged and complicated period of rehabilitation, he has been discharged home; he requires carers due to dyspraxia and is mobilising independently.

摘要

作者报告了一例46岁的业余健美运动员发生动脉粥样硬化性中风的病例,该患者有20年滥用合成代谢 - 肾上腺素能类固醇(AAS)的病史。脑血管意外(CVA)发生在他因急腹症入院的第三周,以及急诊剖腹手术后的第8天。CVA表现为虚脱、全身性癫痫发作、格拉斯哥昏迷评分降低和严重高血压。随后他被收入重症监护病房(ICU),初始检查未明确潜在诊断。在ICU的第4天,临床无明显改善,于是重复进行影像学检查,确定为大脑中动脉区域的左额叶梗死。作者认为CVA是由AAS继发引起的。经过漫长而复杂的康复期后,他已出院回家;由于运动障碍,他需要护理人员,目前能够独立活动。

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本文引用的文献

1
Anabolic steroids: dependence and complications of chronic use.合成代谢类固醇:长期使用的依赖性及并发症
Intern Emerg Med. 2009 Aug;4(4):289-96. doi: 10.1007/s11739-009-0260-5. Epub 2009 May 26.
2
Ischemic stroke related to anabolic abuse.与合成代谢药物滥用相关的缺血性中风。
Clin Neuropharmacol. 2008 Mar-Apr;31(2):80-5. doi: 10.1097/WNF.0b013e3180ed4485.
5
Effects of androgenic-anabolic steroids in athletes.雄激素同化类固醇对运动员的影响。
Sports Med. 2004;34(8):513-54. doi: 10.2165/00007256-200434080-00003.
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Steroid anabolic drugs and arterial complications in an athlete--a case history.
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