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美沙酮替代疗法:经过尝试、检验,是否有效?

Methadone replacement therapy: tried, tested, effective?

作者信息

Robertson J R, Daniels A M

机构信息

Muirhouse Medical Group and Clinical Reader, University of Edinburgh, Scotland, UK.

出版信息

J R Coll Physicians Edinb. 2012 Jun;42(2):133-8. doi: 10.4997/JRCPE.2012.210.

Abstract

Methadone prescription is a controversial topic. While many believe that it is an effective treatment for opiate dependency, others argue that it is not successful in reducing either the addiction or even injecting behaviour. In this debate, Dr Robertson makes the case that methadone has been well tested, is cheap and acceptable to the patient and results in visible improvement. Dr Daniels argues that methadone treatment is philosophically ill-conceived, ethically dubious, and costly. He also highlights evidence that the treatment is potentially harmful to both patients and those in contact with them.

摘要

美沙酮处方是一个有争议的话题。虽然许多人认为它是治疗阿片类药物依赖的有效方法,但也有人认为它在减少成瘾甚至注射行为方面并不成功。在这场辩论中,罗伯逊博士提出,美沙酮已经经过充分测试,价格便宜且患者可接受,并且能带来明显改善。丹尼尔斯博士则认为美沙酮治疗在理念上考虑不周,在伦理上存在疑问且成本高昂。他还强调了一些证据,表明这种治疗对患者及其接触的人都有潜在危害。

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