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[60岁以上法国人群中动脉高血压的发病率]

[Incidence of arterial hypertension in French population after 60 years].

作者信息

Thomas F, Bean K, London G, Danchin N, Pannier B

机构信息

Centre d'investigations préventives et cliniques (IPC), 6, rue La Pérouse, 75116 Paris, France.

出版信息

Ann Cardiol Angeiol (Paris). 2012 Jun;61(3):140-4. doi: 10.1016/j.ancard.2012.04.021. Epub 2012 May 23.

Abstract

OBJECTIVE

To evaluate incidence and determinants of arterial hypertension after 60 years.

METHODS

Four thousand nine hundred and forty one subjects aged 60 years or above (2505 men: 64.2±4.2 years; 2436 women: 64.8±4.3 years) were explored two times at the IPC center, Paris, between 1992 and 2007, and were normotensive at the first visit (V1): systolic BP (SBP) less than 140mmHg and diastolic BP (DBP) less than 90mmHg without treatment. The delay between the two visits was 5.8±2.2 years. At the second visit, population was analysed as normotensives and hypertensives. An age-adjusted Anova compared groups.

RESULTS

In men, incidence of hypertension is 41.5% and 25.9% for isolated systolic hypertension. In women, incidences were 37.8% and 27.8% respectively. Baseline characteristics for V2-hypertensives showed higher SBP, DBP, BMI, heart rate, glycemia, ECG abnormalities thanV2-normotensives but they had lower physical activity. The determinants of hypertension were: SBP, age, BMI, DBP, glycemia, and lack of physical activity for this age class.

CONCLUSION

From 60 years old, 6-year incidence of hypertension is about 40% and 26% for isolated systolic hypertension, this latter being higher in women. Regular physical activity is protective.

摘要

目的

评估60岁后动脉高血压的发病率及决定因素。

方法

1992年至2007年期间,对巴黎IPC中心的4941名60岁及以上受试者(2505名男性:64.2±4.2岁;2436名女性:64.8±4.3岁)进行了两次调查,他们在首次就诊(V1)时血压正常:收缩压(SBP)低于140mmHg且舒张压(DBP)低于90mmHg,未经治疗。两次就诊之间的间隔为5.8±2.2年。在第二次就诊时,将人群分为血压正常者和高血压患者进行分析。采用年龄调整后的方差分析对各组进行比较。

结果

男性高血压发病率为41.5%,单纯收缩期高血压发病率为25.9%。女性发病率分别为37.8%和27.8%。V2高血压患者的基线特征显示,其收缩压、舒张压、体重指数、心率、血糖、心电图异常均高于V2血压正常者,但身体活动较少。高血压的决定因素为:该年龄组的收缩压、年龄、体重指数、舒张压、血糖和缺乏身体活动。

结论

60岁起,高血压6年发病率约为40%,单纯收缩期高血压发病率约为26%,后者在女性中更高。规律的身体活动具有保护作用。

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