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认知缺陷与种族:荷兰早期精神病患者队列研究。

Cognitive deficits and ethnicity: a cohort study of early psychosis patients in The Netherlands.

机构信息

Centre for Early Psychosis, Parnassia Psychiatric Institute, Lijnbaan 4, 2512 VA, The Hague, The Netherlands.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2013 Jan;48(1):37-47. doi: 10.1007/s00127-012-0521-x. Epub 2012 Jun 14.

Abstract

PURPOSE

Incidence rates of psychotic disorders are higher in immigrant groups compared to native populations. This increased risk may partly be explained by misdiagnosis. Neurocognitive deficits are a core feature of psychotic disorders, but little is known about the relationship between migration and cognition in psychotic disorders. We examined whether immigrant patients have cognitive deficits similar to non-immigrant patients, in order to investigate the plausibility of misdiagnosis as explanation for increased incidence rates.

METHODS

Patients who made first contact for non-affective psychotic disorder were assessed in the cognitive domains sustained attention, immediate recall and delayed recall. Immigrant patients were compared to Dutch patients on cognitive performance.

RESULTS

407 Patients diagnosed with a non-affective psychotic disorder completed cognitive assessment (157 Dutch, 250 immigrants). Both Dutch and immigrant patients showed large cognitive deficits. Between-subgroup comparisons revealed large cognitive deficits for immigrants compared to Dutch, especially for immigrants from Morocco, Turkey and other non-Western countries.

CONCLUSIONS

These results indicate that immigrant status is associated with poorer cognitive functioning in early psychosis. The findings argue against diagnostic bias as an explanation for the increased incidence of psychotic disorders in immigrants.

摘要

目的

与本地人群相比,移民群体的精神病发病率更高。这种风险增加的部分原因可能是误诊。神经认知缺陷是精神病的核心特征,但人们对精神病患者的迁移与认知之间的关系知之甚少。我们研究了移民患者是否存在与非移民患者相似的认知缺陷,以探讨误诊作为发病率增加的解释的合理性。

方法

对首次接触非情感性精神病的患者进行了认知领域的持续注意力、即时记忆和延迟记忆评估。将移民患者与荷兰患者的认知表现进行了比较。

结果

407 名被诊断为非情感性精神病的患者完成了认知评估(157 名荷兰人,250 名移民)。荷兰和移民患者均表现出明显的认知缺陷。亚组间比较显示,移民患者的认知缺陷明显大于荷兰患者,尤其是来自摩洛哥、土耳其和其他非西方国家的移民。

结论

这些结果表明,移民身份与早期精神病患者较差的认知功能有关。研究结果排除了诊断偏差是移民中精神病发病率增加的解释。

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