Herrlinger A, Kühn R, Sigel A
Urologische Klinik, Universität Erlangen-Nürnberg.
Helv Chir Acta. 1990 Nov;57(3):477-81.
What is the benefit of an extended dissection of the regional lymph nodes in the treatment of renal cell carcinoma (RCC)? We evaluated the results of 511 consecutive patients which we operated on RCC. The data of 320 patients (SLD) who had an extended dissection of the regional lymph nodes have been compared with those of 191 patients (FLD) who had a dissection of none or only of a few nodes for staging reasons. All patients were nephrectomized under curative intent (M0) with a transabdominal approach. 1. The incidence of N+ in the SLD group was 17.5% and 10% in the FLD group. 2. The overall 5-year survival rates were 58% after FLD and 66% after SLD, the 10-year survival rates 38% after FLD and 54% after SLD (p less than 0.01). 3. The perioperative mortality of patients with extended dissection was 0.9%. We conclude from our data that the extended dissection of the regional lymph nodes significantly improves the prognosis of patients which were operated for RCC.
在肾细胞癌（RCC）治疗中，扩大区域淋巴结清扫术的益处是什么？我们评估了连续接受RCC手术的511例患者的结果。将320例行扩大区域淋巴结清扫术患者（SLD组）的数据与191例因分期原因未行或仅行少数淋巴结清扫术患者（FLD组）的数据进行了比较。所有患者均采用经腹途径，在根治性意图（M0）下行肾切除术。1. SLD组N + 的发生率为17.5%，FLD组为10%。2. FLD组总体5年生存率为58%，SLD组为66%；10年生存率FLD组为38%，SLD组为54%（p小于0.01）。3. 扩大清扫患者的围手术期死亡率为0.9%。我们从数据中得出结论，区域淋巴结扩大清扫术显著改善了接受RCC手术患者的预后。
