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针对边缘型人格障碍患者的危机干预

Crisis interventions for people with borderline personality disorder.

作者信息

Borschmann Rohan, Henderson Claire, Hogg Joanna, Phillips Rachel, Moran Paul

机构信息

Health Service and Population Research Department, Institute of Psychiatry, King’s College London, London, UK.

出版信息

Cochrane Database Syst Rev. 2012 Jun 13(6):CD009353. doi: 10.1002/14651858.CD009353.pub2.

Abstract

BACKGROUND

People with borderline personality disorder (BPD) frequently present to health services in crisis, often involving suicidal thoughts or actions. Despite this, little is known about what constitutes effective management of acute crises in this population.

OBJECTIVES

To review the evidence for the effectiveness of crisis interventions for adults with BPD in any setting. For the purposes of the review, we defined crisis intervention as 'an immediate response by one or more individuals to the acute distress experienced by another individual, which is designed to ensure safety and recovery and lasts no longer than one month.'

SEARCH METHODS

We searched the following databases in September 2011: CENTRAL (The Cochrane Library 2011, Issue 3), MEDLINE (1948 to August Week 5 2011), MEDLINE In Process & Other Non-indexed Citations (8 September 2011), EMBASE (1980 to Week 36 2011), PsycINFO (1806 to September Week 1 2011), CINAHL (1937 to current), Social Services Abstracts (1979 to current), Social Care Online (12 September 2011), Science Citation Index (1970 to current), Social Science Citation Index (1970 to current), Conference Proceedings Citation Index - Science (1990 to current), Conference Proceedings Citation Index - Social Science and Humanities (1990 to current) and ZETOC Conference proceedings (12 September 2011). We searched for dissertations in WorldCat (12 September 2011), Australasian Digital Theses Program (ADTP; 12 September 2011), Networked Digital Library of Theses and Dissertations (NDLTD), 12 September 2011 and Theses Canada Portal (12 September 2011). We searched for trials in the International Clinical Trials Registry Platform (ICTRP) and searched reference lists from relevant literature. We contacted the 10 most published researchers in the field of BPD (as indexed by BioMed Experts), in addition to contacting topic experts, Marsha Linehan, Arnoud Arntz and Paul Links, about ongoing trials and unpublished data.

SELECTION CRITERIA

Randomised controlled trials (RCTs) comparing crisis interventions with usual care or no intervention or a waiting list control for adults of any age with BPD.

DATA COLLECTION AND ANALYSIS

Two authors independently screened titles, abstracts and full-text articles and assessed these against the inclusion criteria.

MAIN RESULTS

The search identified 15 studies, 13 of which we excluded. Reasons for exclusion were: lack of randomisation (N = 8); retrospective design (N = 2); or the intervention was a complex psychological therapy lasting longer than one month (N = 3). We identified two ongoing RCTs that met the inclusion criteria, with a combined predicted sample size of 688. These trials are ongoing and the results are therefore not included in the review, although they will be incorporated into future updates.

AUTHORS' CONCLUSIONS: A comprehensive search of the literature showed that currently there is no RCT-based evidence for the management of acute crises in people with BPD and therefore we could not reach any conclusions about the effectiveness of any single crisis intervention. High-quality, large-scale, adequately powered RCTs in this area are urgently needed.

摘要

背景

边缘型人格障碍(BPD)患者经常在危机状态下寻求医疗服务,这些危机往往涉及自杀念头或行为。尽管如此,对于如何有效管理这一人群的急性危机,我们知之甚少。

目的

回顾在任何环境下针对成年BPD患者进行危机干预有效性的证据。在本综述中,我们将危机干预定义为“一个或多个人对另一个人所经历的急性痛苦做出的即时反应,旨在确保安全和康复,且持续时间不超过一个月”。

检索方法

我们于2011年9月检索了以下数据库:CENTRAL(考克兰图书馆2011年第3期)、MEDLINE(1948年至2011年8月第5周)、MEDLINE在研及其他未索引引文(2011年9月8日)、EMBASE(1980年至2011年第36周)、PsycINFO(1806年至2011年9月第1周)、CINAHL(1937年至今)、社会服务摘要(1979年至今)、社会护理在线(2011年9月12日)、科学引文索引(1970年至今)、社会科学引文索引(1970年至今)、会议论文引文索引 - 科学(1990年至今)、会议论文引文索引 - 社会科学与人文科学(1990年至今)以及ZETOC会议论文集(2011年9月12日)。我们在WorldCat(2011年9月12日)、澳大利亚数字论文项目(ADTP;2011年9月12日)、网络数字论文图书馆(NDLTD,2011年9月12日)以及加拿大论文门户(2011年9月12日)中搜索了学位论文。我们在国际临床试验注册平台(ICTRP)中搜索了试验,并搜索了相关文献的参考文献列表。除了联系主题专家玛莎·莱茵汉、阿诺德·阿恩茨和保罗·林克斯询问正在进行的试验和未发表的数据外,我们还联系了BPD领域发表论文最多的10位研究人员(由生物医学专家索引)。

入选标准

比较危机干预与常规护理或无干预或等待名单对照的随机对照试验(RCT),针对任何年龄的成年BPD患者。

数据收集与分析

两位作者独立筛选标题、摘要和全文文章,并根据纳入标准对其进行评估。

主要结果

检索共识别出15项研究,其中13项被排除。排除原因如下:缺乏随机化(N = 8);回顾性设计(N = 2);或干预是持续时间超过一个月的复杂心理治疗(N = 3)。我们识别出两项符合纳入标准的正在进行的RCT,预计样本量总计688例。这些试验正在进行中,因此结果未纳入本综述,不过它们将被纳入未来的更新版本。

作者结论

对文献的全面检索表明,目前尚无基于RCT的证据可用于管理BPD患者的急性危机,因此我们无法就任何单一危机干预的有效性得出结论。该领域迫切需要高质量、大规模且有足够效力的RCT。

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