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原发性心脏脂肪肉瘤

Primary liposarcoma of the heart.

作者信息

Steger Christina Maria

机构信息

Department of Pathology, Innsbruck Medical University, Innsbruck, Austria.

出版信息

BMJ Case Rep. 2011 May 3;2011:bcr0320114013. doi: 10.1136/bcr.03.2011.4013.

Abstract

The author reports a case of a 64-year-old man, who presented with a 4-week history of dyspnoea and dizziness suffering from a large mass in the pericardium. CT of the chest showed a lobulated mass in the pericardial sac located between the pulmonary veins and the ascending aorta reaching the superior vena cava. The tumour was completely resected and histopathological analysis revealed the tumour to be a well-differentiated lipoma-like and focal sclerosing liposarcoma, which was composed predominantly of adipocytes with hyperchromatic nuclei and eosinophilic-to-vacuolated cytoplasm disrupted by fibrous septa. Two years after initial tumour diagnosis the patient is still alive without signs of tumour recurrence.

摘要

作者报告了一例64岁男性病例,该患者因心包内有一巨大肿块,出现了为期4周的呼吸困难和头晕症状。胸部CT显示心包腔内有一个分叶状肿块,位于肺静脉和升主动脉之间,向上延伸至上腔静脉。肿瘤被完整切除,组织病理学分析显示该肿瘤为高分化脂肪瘤样和局灶性硬化性脂肪肉瘤,主要由脂肪细胞组成,细胞核深染,细胞质呈嗜酸性至空泡状,被纤维间隔分隔。在最初诊断肿瘤两年后,患者仍然存活,没有肿瘤复发的迹象。

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