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腹膜假黏液瘤:播散性腹膜腺黏液瘤变异型。

Pseudomyxoma peritonei: disseminated peritoneal adenomucinosis variant.

作者信息

Pandey Anshuman, Mishra Ashish Kumar

机构信息

Department of Surgical Gastroenterology, Chattrapati Shahuji Maharaj University, Lucknow, India.

出版信息

BMJ Case Rep. 2011 May 3;2011:bcr0720103181. doi: 10.1136/bcr.07.2010.3181.

DOI:10.1136/bcr.07.2010.3181
PMID:22696701
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3089927/
Abstract

Pseudomyxoma peritonei (PMP) is a rare disease and even after advances in its understanding and management it often has a protracted course and multiple recurrences despite aggressive surgery and intraperitoneal chemotherapy. The current preferred treatment of ultraradical surgery and hyperthermic intraperitoneal chemotherapy is associated with considerable morbidity and significant mortality. With better understanding we know that the prognosis of the disease is dependent on the degree of total excision of the disease and type of histology. The authors propose the need to be selective in applying aggressive treatment regimens in all patients with PMP regardless of factors like age, low malignant variants and expected morbidities. Our patient had a good outcome with a conservative approach. However, large studies are needed before reaching a conclusion.

摘要

腹膜假黏液瘤(PMP)是一种罕见疾病,即便在对其认识和治疗方面取得了进展,尽管采取了积极的手术和腹腔内化疗,它通常病程迁延且多次复发。目前首选的超根治性手术和热灌注腹腔内化疗治疗方法伴有相当高的发病率和显著的死亡率。随着认识的加深,我们知道该疾病的预后取决于疾病的完全切除程度和组织学类型。作者提出,对于所有PMP患者,无论年龄、低恶性变体和预期发病率等因素如何,在应用积极的治疗方案时都需要有所选择。我们的患者采用保守方法取得了良好疗效。然而,在得出结论之前还需要进行大量研究。

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本文引用的文献

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Update on the surgical approach to mucocele of the appendix.阑尾黏液囊肿手术治疗进展
J Am Coll Surg. 2006 Apr;202(4):680-4. doi: 10.1016/j.jamcollsurg.2005.12.003. Epub 2006 Feb 17.
2
Elevated tumour markers prior to complete tumour removal in patients with pseudomyxoma peritonei predict early recurrence.腹膜假黏液瘤患者在肿瘤完全切除前肿瘤标志物升高预示早期复发。
Colorectal Dis. 2005 Jul;7(4):382-6. doi: 10.1111/j.1463-1318.2005.00773.x.
3
Cytoreductive surgery with intraperitoneal chemohyperthermia for the treatment of pseudomyxoma peritonei: a prospective study.细胞减灭术联合腹腔内热化疗治疗腹膜假黏液瘤:一项前瞻性研究。
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Long-term survival following treatment of pseudomyxoma peritonei: an analysis of surgical therapy.腹膜假黏液瘤治疗后的长期生存:手术治疗分析
Ann Surg. 2005 Feb;241(2):300-8. doi: 10.1097/01.sla.0000152015.76731.1f.
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Utility of CEA and CA 19-9 tumor markers in diagnosis and prognostic assessment of mucinous epithelial cancers of the appendix.癌胚抗原(CEA)和糖类抗原19-9(CA 19-9)肿瘤标志物在阑尾黏液上皮癌诊断及预后评估中的应用
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Urachal adenocarcinoma in situ with pseudomyxoma peritonei: a case report.原位脐尿管腺癌伴腹膜假黏液瘤:一例报告
J Clin Pathol. 2003 Feb;56(2):152-3. doi: 10.1136/jcp.56.2.152.
7
MUC2 is a molecular marker for pseudomyxoma peritonei.MUC2是腹膜假黏液瘤的分子标志物。
Mod Pathol. 2002 Sep;15(9):958-72. doi: 10.1097/01.MP.0000026617.52466.9F.
8
Morbidity and mortality associated with intraperitoneal chemotherapy for Pseudomyxoma peritonei.与腹膜假黏液瘤腹腔内化疗相关的发病率和死亡率。
Am J Surg. 2002 May;183(5):529-32. doi: 10.1016/s0002-9610(02)00843-7.
9
Cytoreduction including total gastrectomy for pseudomyxoma peritonei.细胞减灭术,包括针对腹膜假黏液瘤的全胃切除术。
Br J Surg. 2002 Feb;89(2):208-12. doi: 10.1046/j.0007-1323.2001.01967.x.
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Pseudomyxoma peritonei.腹膜假黏液瘤
Surgery. 2002 Feb;131(2):230-1. doi: 10.1067/msy.2002.113111.