Hadaki M, Praseedom R, Brais R, See T C, Balan K, Wilson C B
Department of Clinical Oncology, Adeenbrooke's Hospital, Cambridge, UK.
BMJ Case Rep. 2011 May 16;2011:bcr0120113793. doi: 10.1136/bcr.01.2011.3793.
Almost half the patients with colorectal cancer will develop liver metastasis at some stage during their disease. Potentially curative surgical resection is possible in some of these patients. In those patients unsuitable for surgery, treatment with systemic chemotherapy and external radiation therapy is relatively ineffective. Many studies have described the successful use of selective internal radiation therapy (SIRT) with 90Y-SIR-Spheres microspheres in patients with inoperable liver metastasis. The authors report on a patient who has been in complete remission for 1 year after treatment with SIRT.
几乎一半的结直肠癌患者在其病程的某个阶段会发生肝转移。其中一些患者有可能通过手术切除实现治愈。对于那些不适合手术的患者,全身化疗和外照射治疗的效果相对较差。许多研究都描述了90Y-SIR-微球选择性内照射治疗(SIRT)在无法手术切除的肝转移患者中的成功应用。作者报告了一名患者,其在接受SIRT治疗后已完全缓解1年。