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原发性恶性肿瘤全锁骨切除术后的功能和肿瘤学结局。

Functional and oncological outcomes after total claviculectomy for primary malignancy.

作者信息

Li Zhaoxu, Ye Zhaoming, Zhang Miaofeng

机构信息

Department of Orthopaedics, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China.

出版信息

Acta Orthop Belg. 2012 Apr;78(2):170-4.

Abstract

Primary malignancies of the clavicle are very rare, and scarce data are available regarding the functional and oncologic outcome after total claviculectomy. This is a retrospective review of 9 patients with primary clavicular malignancy, between 2000 and 2010, treated with total claviculectomy. There were 5 females and 4 males with a mean age of 29 years (range, 16 to 56). After a mean follow-up period of 46 months (range, 24-102 months) all patients were alive and without local recurrence or metastases. Patients had almost a full range of motion without pain, without significant functional deficit. The mean Constant-Murley score (best possible score = 100) improved from 26 to 79 (p < 0.001), while the VAS for pain improved from 8.7 to 2.4 (p < 0.001). Therefore, total claviculectomy may be a useful salvage procedure for primary clavicular malignancy.

摘要

锁骨原发性恶性肿瘤非常罕见,关于全锁骨切除术后的功能和肿瘤学结果的可用数据很少。这是一项对2000年至2010年间接受全锁骨切除术治疗的9例原发性锁骨恶性肿瘤患者的回顾性研究。其中女性5例,男性4例,平均年龄29岁(范围16至56岁)。平均随访46个月(范围24至102个月)后,所有患者均存活,无局部复发或转移。患者几乎具有全范围的活动且无疼痛,无明显功能缺陷。平均Constant-Murley评分(最佳可能评分为100)从26提高到79(p < 0.001),而疼痛视觉模拟评分(VAS)从8.7提高到2.4(p < 0.001)。因此,全锁骨切除术可能是原发性锁骨恶性肿瘤的一种有用的挽救手术。

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