Radovanovic Ingrid, Queally Joseph, Bahari Syah, Sproule James, McElwain John
Department of Trauma & Orthopaedic Surgery, Adelaide and Meath National Hospital, Dublin, Ireland.
Acta Orthop Belg. 2012 Apr;78(2):187-91.
Currently, there is very limited literature on the effect of long-term anticoagulants on total knee arthroplasty. The primary purpose of this study was to determine the effect of warfarin and clopidogrel on the transfusion rate, intra-operative blood loss, and postoperative blood loss for total knee arthroplasty. The secondary purpose was to determine their effect on post operative wound complications and length of stay. Data was collected retrospectively from medical charts between 2003-2008 and case matched to a control group. The patients on warfarin had a higher rate of blood transfusion, blood loss, and length of hospital stay compared to the clopidogrel and control groups.
目前，关于长期抗凝剂对全膝关节置换术影响的文献非常有限。本研究的主要目的是确定华法林和氯吡格雷对全膝关节置换术的输血率、术中失血量和术后失血量的影响。次要目的是确定它们对术后伤口并发症和住院时间的影响。数据是从2003年至2008年的病历中回顾性收集的，并与对照组进行病例匹配。与氯吡格雷组和对照组相比，服用华法林的患者输血率、失血量和住院时间更高。
