School of Nursing & Midwifery, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia.
Int Wound J. 2013 Aug;10(4):389-96. doi: 10.1111/j.1742-481X.2012.00995.x. Epub 2012 Jun 14.
This study aimed to assess the feasibility of a home-based exercise programme and examine the effects on the healing rates of venous leg ulcers. A 12-week randomised controlled trial was conducted investigating the effects of an exercise intervention compared to a usual care group. Participants in both groups (n = 13) had active venous ulceration and were treated in a metropolitan hospital outpatients clinic in Australia. Data were collected on recruitment from medical records, clinical assessment and questionnaires. Follow-up data on progress in healing and treatments were collected fortnightly for 12 weeks. Calf muscle pump function data were collected at baseline and 12 weeks from recruitment. Range of ankle motion data were collected at baseline, 6 and 12 weeks from recruitment. This pilot study indicated that the intervention was feasible. Clinical significance was observed in the intervention group with a 32% greater decrease in ulcer size (P = 0·34) than the usual care group, and a 10% (P = 0·74) improvement in the number of participants healed in the intervention group compared to the usual care group. Significant differences between groups over time were observed in calf muscle pump function parameters [ejection fraction (P = 0·05), residual volume fraction (P = 0·04)] and range of ankle motion (P = 0·01). This pilot study is one of the first to examine and measure clinical healing rates for participants involved in a home-based progressive resistance exercise programme. Further research is warranted with a larger multi-site study.
本研究旨在评估基于家庭的运动方案的可行性,并研究其对静脉性腿部溃疡愈合率的影响。这是一项为期 12 周的随机对照试验,旨在调查运动干预与常规护理组的效果。两组参与者(n=13)均患有活动性静脉溃疡,在澳大利亚的一家都市医院门诊接受治疗。招募时从病历、临床评估和问卷调查中收集数据。在 12 周的时间里,每两周收集一次愈合进展和治疗情况的随访数据。在招募时和 12 周时收集小腿肌肉泵功能数据。在招募时、6 周和 12 周时收集踝关节活动范围数据。这项初步研究表明该干预措施是可行的。干预组的临床意义明显,溃疡面积缩小了 32%(P=0·34),比常规护理组更大,与常规护理组相比,干预组有 10%(P=0·74)的参与者愈合。小腿肌肉泵功能参数[射血分数(P=0·05)、残余容量分数(P=0·04)]和踝关节活动范围(P=0·01)在组间随时间的差异具有统计学意义。这项初步研究是首批对参与基于家庭的渐进式抗阻运动方案的参与者的临床愈合率进行检查和测量的研究之一。需要进一步进行更大规模的多中心研究。