Hamm J C, DeFranzo A J, Argenta L C, White W
Department of Pathology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, N.C. 27103.
J Hand Surg Am. 1990 Nov;15(6):980-6. doi: 10.1016/0363-5023(90)90028-p.
Keratoacanthoma is usually considered a benign self-limiting lesion. First described in 1888 by Hutchinson, it most commonly involves the face and hands. It is usually controlled by complete soft tissue excision. A variant, subungual keratoacanthoma, affects bone by pressure erosion of the distal phalangeal tip. We report a case of keratoacanthoma clinically involving a metacarpal and phalanges with a radiologic and physical appearance at variance with previous reports. After multiple recurrences following erosion and cryosurgery, as well as attempted digit salvage with Mohs' surgery, ray amputation was required. The world literature pertaining to keratoacanthoma is reviewed and discussed.
角化棘皮瘤通常被认为是一种良性的自限性病变。1888年由哈钦森首次描述，它最常累及面部和手部。通常通过完整的软组织切除来控制。一种变异型，即甲下角化棘皮瘤，可通过远端指骨尖端的压力侵蚀影响骨骼。我们报告一例角化棘皮瘤，临床上累及掌骨和指骨，其影像学和体格检查表现与既往报道不同。在侵蚀和冷冻手术后多次复发，以及尝试用莫氏手术挽救手指后，需要进行截指手术。对有关角化棘皮瘤的世界文献进行了回顾和讨论。
