el-Labban N G, Harris M, Hopper C, Barber P
Institute of Dental Surgery, Eastman Dental Hospital, London, England.
J Oral Pathol Med. 1990 Oct;19(9):423-5. doi: 10.1111/j.1600-0714.1990.tb00872.x.
The masseter and temporalis muscles were studied ultrastructurally in eight cases suffering from restricted mouth opening and TMJ ankylosis. The changes varied from slight degeneration of muscle fibers, such as accumulation of lipid or lipofuscin deposits, Z-band streaming and derangement of myofilaments, in one case to moderate or severe changes of muscle atrophy and necrosis in the remaining seven cases. Nemaline bodies were also observed in one of these seven cases. In addition to these muscle changes neural degeneration especially of myelinated nerves were found in three of the cases studied. The present findings showed that in spite of the diversity of the underlying factors affecting the joint, there was many similarities in the changes observed within the muscle. It is postulated that these degenerative muscle changes probably play an important role in restricted mouth opening and TMJ ankylosis, and that some of these muscle pathology may be the result of neural involvement.
对8例张口受限和颞下颌关节强直患者的咬肌和颞肌进行了超微结构研究。变化程度不一，1例表现为肌纤维轻度退变，如脂质或脂褐素沉积、Z带流和肌丝排列紊乱，其余7例则表现为中度或重度的肌肉萎缩和坏死。在这7例中的1例还观察到棒状体。除了这些肌肉变化外，在所研究的3例中还发现了神经退变，尤其是有髓神经的退变。目前的研究结果表明，尽管影响关节的潜在因素多种多样，但在肌肉内观察到的变化有许多相似之处。据推测，这些肌肉退行性变化可能在张口受限和颞下颌关节强直中起重要作用，并且其中一些肌肉病变可能是神经受累的结果。
