Miranda Suzette G, Kashani-Sabet Mohammed, Zedek Daniel, McCalmont Timothy H, Leong Stanley P L
Department of Surgery, University of California at San Francisco, San Francisco, California, USA.
BMJ Case Rep. 2011 Mar 29;2011:bcr0920103343. doi: 10.1136/bcr.09.2010.3343.
Cutaneous melanoma is extremely uncommon in children. Further, Asian-Americans appear to be at decreased risk for cutaneous melanoma. The authors present the case of a prepubescent Asian girl who presents with the rare spitzoid variant of cutaneous melanoma. The patient is a 4-year-old girl of Chinese descent who presented with a red, raised nodule, which increased in size over a 3-month period. She underwent wide local excision with sentinel lymph node dissection. On histopathologic analysis, she was found to have Spitzoid melanoma of childhood/adolescence. Spitzoid melanoma in children is rare and incompletely understood. A recent systematic review was only able to identify 82 such cases published over a 57-year period. To our knowledge, this is the first report of Spitzoid melanoma in a paediatric age patient of Asian descent. While this clearly is an uncommon demographic, it seeks to highlight important differences in racial predilection for Spitzoid melanoma.
皮肤黑色素瘤在儿童中极为罕见。此外，亚裔美国人患皮肤黑色素瘤的风险似乎较低。作者报告了一例青春期前的亚裔女孩，她患有一种罕见的皮肤黑色素瘤的斯皮茨样变种。该患者是一名4岁的华裔女孩，她出现了一个红色的、隆起的结节，在3个月内大小增加。她接受了广泛的局部切除并进行了前哨淋巴结清扫。经组织病理学分析，发现她患有儿童/青少年期斯皮茨样黑色素瘤。儿童期斯皮茨样黑色素瘤很罕见，人们对此了解并不完全。最近的一项系统综述仅能识别出在57年期间发表的82例此类病例。据我们所知，这是第一例关于亚裔血统儿科患者的斯皮茨样黑色素瘤的报告。虽然这显然是一个不常见的人群，但它旨在突出斯皮茨样黑色素瘤在种族偏好方面的重要差异。
