Department of Obstetrics and Gynecology, Kuo General Hospital, Tainan, Taiwan.
Andrologia. 2013 Apr;45(2):140-4. doi: 10.1111/j.1439-0272.2012.01320.x. Epub 2012 Jun 18.
Structural rearrangement in the Y chromosome is closely involved in spermatogenesis. However, several Y chromosome variants may have no deleterious effects on male reproduction. Here, we report two cases of Y chromosomal duplication from incidental findings. Their FISH analysis revealed direct duplication of large segments of short and long arms of the Y chromosome. Nearly two intact Y chromosomes were carried in these two cases with normal phenotype.
Y 染色体结构重排与精子发生密切相关。然而，一些 Y 染色体变体可能对男性生殖没有有害影响。在这里，我们报告了两例偶然发现的 Y 染色体重复病例。他们的 FISH 分析显示，Y 染色体短臂和长臂的大片段发生了直接重复。这两例患者携带了几乎完整的两条 Y 染色体，表型正常。
