Frauchiger B
Medizinische Klinik, Kantonsspital Luzern.
Schweiz Rundsch Med Prax. 1990 Dec 11;79(50):1560-3.
Strict control of risk factors and walking exercise are the basics to any medical treatment of arterial obstructive disease of the extremities. The benefit of platelet-aggregation inhibitors is well established. Acetylsalicylic acid slows the progression of recurrence of thrombotic occlusion after endarterectomy or percutaneous transluminal angioplasty in the femoral blood stream. Long-term oral anticoagulants are indicated after bypass surgery. Prostaglandin E1 and high-energy phosphates are of proven benefit in patients with pain at rest. Vasoactive drugs such as Dipyridamole are still controversial.
严格控制危险因素和进行步行锻炼是肢体动脉阻塞性疾病任何医学治疗的基础。血小板聚集抑制剂的益处已得到充分证实。乙酰水杨酸可减缓股动脉血流内膜切除术或经皮腔内血管成形术后血栓闭塞复发的进程。旁路手术后需使用长期口服抗凝剂。前列腺素E1和高能磷酸盐对静息痛患者已证实有益。双嘧达莫等血管活性药物仍存在争议。