Wafula E M, Onyango F E, Mirza W M, Macharia W M, Wamola I, Ndinya-Achola J O, Agwanda R, Waigwa R N, Musia J
Department of Paediatrics, University of Nairobi, Kenya.
Rev Infect Dis. 1990 Nov-Dec;12 Suppl 8:S1035-8. doi: 10.1093/clinids/12.supplement_8.s1035.
The epidemiology of acute respiratory tract infection (ARI) was investigated in a rural community 80 km north of Nairobi, Kenya. This research was conducted prospectively on 250 families with 470 children less than 5 years of age who were contacted every 8 days during the 3-year study. The yearly incidence of respiratory tract infections decreased from 5.2 to 3.4 during the study; less than 5% of these infections involved the lower respiratory tract. The incidence was inversely related to age, and the illnesses were generally mild and brief in length. Fifteen children died during the study period. The precise causes of death are unknown, but respiratory infections possibly played a role in most cases. This study emphasizes the importance of determining the risk factors responsible for unusually severe morbidity and high mortality in children with ARI in developing countries.
在肯尼亚内罗毕以北80公里处的一个农村社区，对急性呼吸道感染（ARI）的流行病学情况展开了调查。这项前瞻性研究针对250个家庭中470名5岁以下儿童展开，在为期3年的研究中，每8天与这些家庭进行一次联系。在研究期间，呼吸道感染的年发病率从5.2降至3.4；这些感染中不到5%累及下呼吸道。发病率与年龄呈负相关，疾病通常症状轻微且病程短暂。在研究期间有15名儿童死亡。确切死因不明，但在大多数病例中，呼吸道感染可能起到了一定作用。这项研究强调了确定发展中国家ARI患儿中导致异常严重发病和高死亡率的风险因素的重要性。
