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立陶宛癌症发病率和死亡率的教育不平等:一项记录链接研究。

Educational inequalities in cancer incidence and mortality in Lithuania: a record linkage study.

机构信息

Lithuanian Cancer Registry, Institute of Oncology, Vilnius University, Vilnius, Lithuania.

出版信息

Cancer Epidemiol. 2012 Oct;36(5):e279-83. doi: 10.1016/j.canep.2012.05.009. Epub 2012 Jun 15.

Abstract

BACKGROUND

The aim of this study is to describe associations between incidence and mortality by major cancer sites and education in Lithuania.

METHODS

The study is based on the linkage between all records of the 2001 population census and all records from Lithuanian Cancer Registry (cancer incidence) and Statistics Lithuania (deaths) for the period between 1 July 2001 and 31 December 2004. Education-specific incidence and mortality rate ratios were estimated by means of multivariate Poisson regression models.

RESULTS

We found both the positive and inverse educational gradients in cancer incidence and mortality. The risk of developing cancer (all sites) was lower among men and women with the lowest education, whereas cancer mortality was higher among lower educated men. The higher educational level was also associated with an increased risk of prostate cancer among men and an increased risk of breast cancer among women. However, prostate cancer mortality was the highest in the lowest education group, whereas breast cancer mortality among women did not show any statistically significant differences. Lower educated men had significantly higher incidence and mortality due to lung and stomach cancers. Strikingly high incidence and mortality due to cervix cancer was observed among women with secondary and lower than secondary education.

CONCLUSION

The results point to inequalities in early diagnosis and survival from cancer and failures ensuring equal access to medical care. Further more in-depth studies are needed in order to understand the nature and determinants of these inequalities.

摘要

背景

本研究旨在描述立陶宛主要癌症部位的发病率和死亡率与教育之间的关联。

方法

该研究基于 2001 年人口普查的所有记录与立陶宛癌症登记处(癌症发病率)和立陶宛统计局(死亡率)之间的记录之间的联系,研究时间为 2001 年 7 月 1 日至 2004 年 12 月 31 日。通过多变量泊松回归模型来估计特定教育的发病率和死亡率比值。

结果

我们发现癌症发病率和死亡率均存在正相关和负相关的教育梯度。受教育程度最低的男性和女性患癌症(所有部位)的风险较低,而受教育程度较低的男性癌症死亡率较高。较高的教育水平也与男性前列腺癌风险增加和女性乳腺癌风险增加有关。然而,前列腺癌死亡率在受教育程度最低的人群中最高,而女性乳腺癌死亡率则没有统计学上的显著差异。受教育程度较低的男性患肺癌和胃癌的发病率和死亡率明显较高。受中等和低于中等教育程度的女性宫颈癌发病率和死亡率极高。

结论

研究结果表明,在癌症的早期诊断和生存方面存在不平等现象,并且在确保平等获得医疗保健方面存在失败。需要进一步进行更深入的研究,以了解这些不平等现象的性质和决定因素。

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