Sasaki Yasuhiro, Okuyama Manabu, Hibino Masanori, Tenma Kazuo, Nakamura Masaaki
Dept. of Surgery, Ogachi Chuo Hospital.
Gan To Kagaku Ryoho. 2012 Jun;39(6):1005-8.
We report an 84-year-old woman with an ulcerated tumor of her right breast. The histological examination showed invasive ductal carcinoma, ER (allred-score 8), PgR (allred-score 0), and HER2 (0). Computed tomography and bone scintigraphy showed no distant metastases. She was diagnosed with right locally advanced breast cancer (cT4bN2aM0, stageIIIB) and received hormone therapy with letrozole. One year after, the carcinoma was reduced in size and the skin ulcer had disappeared. Two years later, the carcinoma had grown back slightly, but the skin ulcer was still undetectable. Hormone therapy alone was considered useful for treatment of elderly locally advanced breast cancer patients.
我们报告了一位84岁患有右乳溃疡性肿瘤的女性。组织学检查显示为浸润性导管癌,雌激素受体(Allred评分8分),孕激素受体(Allred评分0分),人表皮生长因子受体2(0)。计算机断层扫描和骨闪烁显像未显示远处转移。她被诊断为右局部晚期乳腺癌(cT4bN2aM0,IIIB期),并接受了来曲唑激素治疗。一年后,癌灶体积缩小,皮肤溃疡消失。两年后,癌灶稍有复发,但皮肤溃疡仍未检出。单纯激素治疗被认为对老年局部晚期乳腺癌患者的治疗有效。