Aomatsu Naoki, Kashiwagi Shinichiro, Asano Yuka, Morisaki Tamami, Nakamura Masanori, Kawajiri Hidemi, Takashima Tsutomu, Onoda Naoyoshi, Ishikawa Tetsuro, Hirakawa Kosei
Dept. of Surgical Oncology, Osaka City University Graduate School of Medicine, Japan.
Gan To Kagaku Ryoho. 2012 Nov;39(12):2042-4.
A 104-year-old female patient with a left breast mass was admitted to our hospital. Ultrasonography showed an irregular and low-echoic mass of about 2.4×2.4×1.4 cm size in the left breast EAC area. Core needle biopsy examination indicated invasive ductal carcinoma of the breast: ER (+), PR (+), and HER2 (-). An overall examination did not show a distant metastasis. We diagnosed her with left breast cancer(luminal A type) T2N0M0, stage IIA. We administered anastrozole at a dose of 1 mg/day. After 6 months, the primary tumor diameter was reduced to 2.1 cm, and the effect of anastrozole was considered a clinical partial response. The patient did not experience any adverse events during treatment. The partial response was maintained for about 2 years. We experienced a successful case of a super-elderly breast cancer patient treated with anastrozole. We conclude that hormone therapy is a useful treatment for super-elderly postmenopausal women with estrogen receptor-positive breast cancer.
一名104岁的左乳肿物女性患者入住我院。超声检查显示左乳EAC区域有一个大小约为2.4×2.4×1.4 cm的不规则低回声肿物。粗针穿刺活检检查提示乳腺浸润性导管癌:ER(+),PR(+),HER2(-)。全面检查未显示远处转移。我们诊断她为左乳腺癌(luminal A型)T2N0M0,IIA期。我们给予阿那曲唑1 mg/天的剂量。6个月后,原发肿瘤直径缩小至2.1 cm,阿那曲唑的疗效被认为是临床部分缓解。患者在治疗期间未出现任何不良事件。部分缓解维持了约2年。我们经历了一例用阿那曲唑治疗的超高龄乳腺癌患者的成功病例。我们得出结论,激素治疗对于雌激素受体阳性的超高龄绝经后乳腺癌女性是一种有效的治疗方法。