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止血检测中样本处理、运输和存储的质量标准。

Quality standards for sample processing, transportation, and storage in hemostasis testing.

机构信息

Esoterix Inc., Englewood, Colorado 80112, USA.

出版信息

Semin Thromb Hemost. 2012 Sep;38(6):576-85. doi: 10.1055/s-0032-1319768. Epub 2012 Jun 16.

DOI:10.1055/s-0032-1319768
PMID:22706973
Abstract

Samples for hemostasis testing drawn into sodium citrate anticoagulant are vulnerable to the effects of preanalytical variables associated with sample processing, transportation, and storage. These variables include the temperature at which samples are transported and stored; the stability of the samples once processed; whether maintained at room temperature, refrigerated, or frozen; methods of centrifugation; as well as the potential impact of using an automated line. Acknowledgment of these variables, as well as understanding their potential impact on assay results, is imperative to the reporting of high quality and accurate results. This article discusses the preanalytical issues associated with sample processing, transportation, and storage and also presents the ideal conditions for sample handling.

摘要

用柠檬酸钠抗凝剂采集的止血检测样本容易受到与样本处理、运输和储存相关的分析前变量的影响。这些变量包括样本运输和储存的温度;样本处理后是否稳定;是否保持室温、冷藏或冷冻;离心的方法;以及使用自动化流水线的潜在影响。承认这些变量,并了解它们对检测结果的潜在影响,对于报告高质量和准确的结果至关重要。本文讨论了与样本处理、运输和储存相关的分析前问题,并提出了样本处理的理想条件。

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