Sarkar Dipankar, Sarkar Shruti, Anand Shweta, Kapoor Anju
Department of Pediatrics, People's College of Medical Science and Research Centre, Bhanpur, Bhopal, Madhya Pradesh, India.
BMJ Case Rep. 2011 Feb 15;2011:bcr1020103420. doi: 10.1136/bcr.10.2010.3420.
Acute respiratory distress syndrome (ARDS) is an acute respiratory condition caused by various pulmonary and extrapulmonary conditions including H1N1 virus infection. ARDS has a high mortality worldwide and in India various studies suggest that mortality in children is as high as 73-75%. Different lung protective ventilation strategies have recently been adopted to reduce mortality. The authors report a successful outcome in a 3.5-year-old child with ARDS secondary to H1N1 infection following use of a very low tidal volume (4-6 ml/kg) along with high positive end-expiratory pressure breathing and prone ventilation. As far as we are aware, this is the first case report of a successful outcome in a child with ARDS secondary to H1N1 in India.
急性呼吸窘迫综合征(ARDS)是一种由多种肺部和肺外疾病引起的急性呼吸疾病,包括H1N1病毒感染。ARDS在全球范围内死亡率很高,在印度,多项研究表明儿童死亡率高达73%-75%。最近采用了不同的肺保护性通气策略以降低死亡率。作者报告了一名3.5岁患有继发于H1N1感染的ARDS儿童,在使用极低潮气量(4-6毫升/千克)以及高呼气末正压通气和俯卧位通气后获得成功治疗的病例。据我们所知,这是印度首例继发于H1N1的ARDS儿童成功治疗的病例报告。