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CrossTalk proposal: Most of the cardiovascular consequences of OSA are due to increased sympathetic activity.

作者信息

Kohler Malcolm, Stradling John R

机构信息

Sleep Disorders Centre and Pulmonary Division, University Hospital of Zurich, Zurich, Switzerland.

出版信息

J Physiol. 2012 Jun 15;590(12):2813-5; discussion 2823. doi: 10.1113/jphysiol.2012.229633.

DOI:10.1113/jphysiol.2012.229633
PMID:22707583
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3448139/
Abstract
摘要

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本文引用的文献

1
Effects of continuous positive airway pressure therapy withdrawal in patients with obstructive sleep apnea: a randomized controlled trial.持续气道正压通气治疗撤机对阻塞性睡眠呼吸暂停患者的影响：一项随机对照试验。
Am J Respir Crit Care Med. 2011 Nov 15;184(10):1192-9. doi: 10.1164/rccm.201106-0964OC.
2
Heart rate: a forgotten link in coronary artery disease?心率：冠心病中被遗忘的一环？
Nat Rev Cardiol. 2011 Apr 26;8(7):369-79. doi: 10.1038/nrcardio.2011.58.
3
Mechanisms of vascular damage in obstructive sleep apnea.阻塞性睡眠呼吸暂停中的血管损伤机制。
Nat Rev Cardiol. 2010 Dec;7(12):677-85. doi: 10.1038/nrcardio.2010.145.
4
Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the sleep heart health study.前瞻性研究阻塞性睡眠呼吸暂停与冠心病和心力衰竭事件的关系：睡眠心脏健康研究。
Circulation. 2010 Jul 27;122(4):352-60. doi: 10.1161/CIRCULATIONAHA.109.901801. Epub 2010 Jul 12.
5
14 nights of intermittent hypoxia elevate daytime blood pressure and sympathetic activity in healthy humans.14 个晚上的间歇性低氧会提高健康人体白天的血压和交感神经活动。
Eur Respir J. 2011 Jan;37(1):119-28. doi: 10.1183/09031936.00204209. Epub 2010 Jun 4.
6
Limitations of the usual blood-pressure hypothesis and importance of variability, instability, and episodic hypertension.通常的血压假说的局限性以及变异性、不稳定性和间歇性高血压的重要性。
Lancet. 2010 Mar 13;375(9718):938-48. doi: 10.1016/S0140-6736(10)60309-1.
7
Intermittent hypoxia-mediated plasticity of acute O2 sensing requires altered red-ox regulation by HIF-1 and HIF-2.间歇性低氧介导的急性氧感知可塑性需要HIF-1和HIF-2改变氧化还原调节。
Ann N Y Acad Sci. 2009 Oct;1177:162-8. doi: 10.1111/j.1749-6632.2009.05034.x.
8
QRISK or Framingham for predicting cardiovascular risk?使用QRISK评分还是弗雷明汉风险评估法来预测心血管风险？
BMJ. 2009 Jul 7;339:b2673. doi: 10.1136/bmj.b2673.
9
The role of cardiac autonomic function in hypertension and cardiovascular disease.心脏自主神经功能在高血压和心血管疾病中的作用。
Curr Hypertens Rep. 2009 Jun;11(3):199-205. doi: 10.1007/s11906-009-0035-4.
10
Cardiovascular and cerebrovascular responses to acute hypoxia following exposure to intermittent hypoxia in healthy humans.健康人暴露于间歇性低氧后对急性低氧的心血管和脑血管反应。
J Physiol. 2009 Jul 1;587(Pt 13):3287-99. doi: 10.1113/jphysiol.2009.171553. Epub 2009 May 5.