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弥漫性大B细胞淋巴瘤:严重耳痛和面神经麻痹的罕见病因。

Diffuse large B-cell lymphoma: an unusual cause of severe otalgia and facial palsy.

作者信息

Reddy Udaya, Bewick Jessica, Good Catriona, Chevassut Timothy, Das-Purkayastha Prodip K

机构信息

Department of Otolaryngology, Brighton and Sussex University Hospitals, Brighton, UK.

出版信息

BMJ Case Rep. 2012 Jun 14;2012:bcr0120125572. doi: 10.1136/bcr.01.2012.5572.

DOI:10.1136/bcr.01.2012.5572
PMID:22707677
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4543236/
Abstract

An elderly woman, two months after chemotherapy for diffuse large B-cell lymphoma, presented with left-sided otalgia, discharge and facial nerve palsy. MRI showed an active left mastoid infection with an ear canal lesion, likely to be a cholesteatoma. However, a biopsy of the mass showed recurrent high-grade lymphoma. Following diagnosis, the patient opted for palliative care within the community and consequently passed away a few weeks later.

摘要

一名老年女性,在接受弥漫性大B细胞淋巴瘤化疗两个月后,出现左侧耳痛、流脓及面神经麻痹。磁共振成像(MRI)显示左侧乳突有活动性感染,并伴有耳道病变,可能为胆脂瘤。然而,对该肿物进行活检显示为复发性高级别淋巴瘤。确诊后,患者选择在社区接受姑息治疗,几周后不幸去世。

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BMJ Case Rep. 2012 Jun 14;2012:bcr0120125572. doi: 10.1136/bcr.01.2012.5572.
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本文引用的文献

1
De novo CD5-positive diffuse large B-cell lymphoma of the temporal bone presenting with an external auditory canal tumor.颞骨原发性CD5阳性弥漫性大B细胞淋巴瘤伴外耳道肿瘤
Intern Med. 2006;45(11):733-7. doi: 10.2169/internalmedicine.45.1671. Epub 2006 Jul 3.
2
Primary central nervous system lymphomas (PCNSL): MRI features at presentation in 100 patients.原发性中枢神经系统淋巴瘤(PCNSL):100例患者初诊时的MRI特征
J Neurooncol. 2005 Apr;72(2):169-77. doi: 10.1007/s11060-004-3390-7.
3
B-cell lymphoma of the external auditory meatus.
J Laryngol Otol. 2002 Jan;116(1):39-41. doi: 10.1258/0022215021910096.
4
Lymphoma in the ear.耳部淋巴瘤
ORL J Otorhinolaryngol Relat Spec. 2000 Sep-Oct;62(5):274-7. doi: 10.1159/000027759.
5
[Petrous bone tumors: primary non-Hodgkin lymphoma of the inner ear canal and cerebellopontile angle].[岩骨肿瘤:内耳道及桥小脑角原发性非霍奇金淋巴瘤]
Laryngorhinootologie. 1997 Oct;76(10):625-8. doi: 10.1055/s-2007-997490.
6
The variable MR appearance of primary lymphoma of the central nervous system: comparison with histopathologic features.中枢神经系统原发性淋巴瘤的磁共振成像表现多样:与组织病理学特征的比较
AJNR Am J Neuroradiol. 1997 Mar;18(3):563-72.