巨细胞病毒感染性小肠结肠炎导致的婴儿死亡。
Infant death due to CMV enterocolitis.
作者信息
Refai Zafer, Nicholls Stuart, Garg Anil
机构信息
Trevor Mann Baby Unit, Royal county Sussex hospital, Brighton, UK.
出版信息
BMJ Case Rep. 2012 Jun 14;2012:bcr1120115080. doi: 10.1136/bcr.11.2011.5080.
Abstract
An infant was admitted with symptoms of diarrhoea and vomiting. After initial improvement she unexpectedly died. Postmortem confirmed a diagnosis of cytomegalovirus (CMV) enterocolitis. The authors report this case and review other published cases of immunocompetent infants who presented with this infection. Clinicians should consider stool CMV PCR test or referral for endoscopy and biopsy in young babies who present with profuse and prolonged episodes of diarrhoea. The value of ganciclovir in immunocompetent infants who suffer with CMV gastrointestinal involvement is still not clear.
摘要
一名婴儿因腹泻和呕吐症状入院。最初病情有所改善后，她意外死亡。尸检确诊为巨细胞病毒（CMV）小肠结肠炎。作者报告了该病例，并回顾了其他已发表的免疫功能正常婴儿感染此病毒的病例。对于出现大量且持续腹泻的幼儿，临床医生应考虑进行粪便CMV聚合酶链反应检测或转诊进行内镜检查及活检。更昔洛韦在免疫功能正常但患有CMV胃肠道感染的婴儿中的价值仍不明确。
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