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[凝血障碍导致的肾移植失败]

[Kidney graft loss as a result of coagulation disorders].

作者信息

Kulik Agnieszka

机构信息

Warszawski Uniwersytet Medyczny, Katedra i Klinika Chirurgii Ogólnej i Transplantacyjnej.

出版信息

Pol Merkur Lekarski. 2012 Apr;32(190):256-9.

Abstract

Renal transplantation is a method of choice in the treatment of endstage kidney insufficiency resulting in improved survival and better quality of life. Advances in immunosuppresive therapy, diagnosis and treatment of infective complications, studies on ischemic injury of transplanted organ and preservation show constant improvement in terms of short and long-term results. Early kidney graft loss resulting from thrombotic complications is rare and still challenging for transplantologists. Renal vein thrombosis is responsible for 2-7% cases of early graft loss. Selecting a subset of patients threatened with thromboembolic complications will allow for starting adequate prophylaxis, or early treatment preventing from complications including graft loss. In this paper we tried to summarize the current state of knowledge regarding venous and arterial thrombosis after renal transplantation.

摘要

肾移植是治疗终末期肾功能不全的首选方法,可提高生存率并改善生活质量。免疫抑制治疗、感染性并发症的诊断与治疗、移植器官缺血损伤及保存方面的研究进展,使得短期和长期疗效不断改善。血栓形成并发症导致的早期肾移植失败较为罕见,但对移植医生来说仍是一项挑战。肾静脉血栓形成导致2%至7%的早期移植失败病例。选择有血栓栓塞并发症风险的患者亚组,有助于启动适当的预防措施或早期治疗,防止包括移植失败在内的并发症。在本文中,我们试图总结肾移植后静脉和动脉血栓形成的当前知识状况。

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