Durocher A, Ballet J J, Pirot J, Granier F, Bauters F, Wattel F
Sem Hop. 1979;55(19-20):1008-10.
The occurence of hypercalcemia appears to be unusual in leukemia. The mechanisms are numerous: secretion of PTH of PTH like substance, prostaglandin E2 or vitamin D like sterols. The reported case is one of lymphoblastic acute leukemia and hypercalcemia associated with osteoclast activating factor secreted by leukemic cells. In this patient the serum levels calcium closely paralleled the course of acute leukemia.
高钙血症在白血病中似乎不常见。其机制多种多样:甲状旁腺激素或类甲状旁腺物质、前列腺素E2或类维生素D固醇的分泌。报道的病例是一例急性淋巴细胞白血病合并高钙血症,与白血病细胞分泌的破骨细胞激活因子有关。在该患者中,血清钙水平与急性白血病的病程密切平行。