Trompoukis P, Papantoniou N, Chlapoutaki C, Mesogitis S, Antsaklis A
1st Department of Obstetrics and Gynecology, University of Athens, Alexandra Hospital, Athens, Greece.
J Matern Fetal Neonatal Med. 2012 Nov;25(11):2363-8. doi: 10.3109/14767058.2012.696161. Epub 2012 Jun 21.
The aim of this study is to emphasize on the diagnostic effectiveness of fetal MRI that led to increased utilization in fetal medicine as well as its value in prognosis and decision making in the modern obstetric practice.
One hundred five (n = 105) pregnant women were referred for a fetal MRI examination after a high detailed ultrasound examination revealed a fetal abnormality. Fetal MRI was performed using 1, 5 Tesla units, with T1, T2-weighted and diffusion-weighted images. The findings were analyzed in comparison to the previous ultrasound findings, according to the fetal organ affected and the value of the MRI for therapeutic decision making was addressed. A statistical analysis was performed.
The fetal MRI provides a more accurate diagnosis compared to ultrasound examination, and when the ultrasound detects fetal anomalies, the MRI can efficiently either confirm or reject the finding, proving its high value for prenatal diagnosis and perinatal and management. The sensitivity, specificity and positive predictive value of fetal MRI as a screening tool approaches 100%.
Despite the fact that ultrasound is the method of choice for fetal screening, MRI can add up significantly to the diagnosis and management of congenital abnormalities and the indications for MRI continue to increase as new sequences and shorter acquisition times evolve.
本研究旨在强调胎儿磁共振成像(MRI)的诊断有效性,其在胎儿医学中的应用日益增加,以及在现代产科实践中其在预后和决策方面的价值。
在高分辨率超声检查发现胎儿异常后,105名孕妇被转诊进行胎儿MRI检查。使用1.5特斯拉设备进行胎儿MRI检查,获取T1、T2加权和扩散加权图像。根据受影响的胎儿器官,将检查结果与先前的超声检查结果进行比较分析,并探讨MRI在治疗决策中的价值。进行了统计分析。
与超声检查相比,胎儿MRI能提供更准确的诊断。当超声检测到胎儿异常时,MRI能够有效地证实或排除该发现,证明其在产前诊断、围产期及管理方面具有很高的价值。胎儿MRI作为一种筛查工具,其敏感性、特异性和阳性预测值接近100%。
尽管超声是胎儿筛查的首选方法,但MRI在先天性异常的诊断和管理方面能显著提供补充,随着新序列和更短采集时间的发展,MRI的应用指征持续增加。