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[神经源性胃良性肿瘤]

[Benign tumors of the stomach of neurogenic origin].

作者信息

Roseano M, Obersnu F

机构信息

Istituto di Clinica Chirurgica, Università degli Studi di Trieste.

出版信息

Ann Ital Chir. 1990 Mar-Apr;61(2):147-51; discussion 152.

PMID:2270882
Abstract

The benign tumours of the stomach are statistically 1-4% of gastric tumours. Progress in diagnostic is in relation with new immuno-histochemical methods and modern radiologic and endoscopic studies. The histopathologic findings are very important for differential diagnosis with benign gastric tumours of mesenchymal origin, specially leiomyomas. Areas of malignant degeneration are sometimes localized in benign gastric tumours of nervous origin. Only in these situations is necessary mayor radical surgery, as gastro-duodenal resection or a total gastrectomy. The authors, in a personal case series of 30 benign gastric tumours, illustrated 5 cases of benign tumours of nervous origin of the stomach. The histologic findings of these cases, all treated with surgical excision, are: one malignant neurinoma, two neurofibromas and two benign schwannomas. In the case of malignant neurinoma has been necessary reinterventions for recurrence. In spite of surgical and chemotherapeutic treatment the patient died for abdominal and hepatic metastasis.

摘要

胃良性肿瘤在统计学上占胃肿瘤的1% - 4%。诊断方面的进展与新的免疫组织化学方法以及现代放射学和内镜研究有关。组织病理学发现对于与间叶组织起源的胃良性肿瘤(特别是平滑肌瘤)进行鉴别诊断非常重要。神经起源的胃良性肿瘤有时会出现恶性变区域。只有在这些情况下才需要进行较大范围的根治性手术,如胃十二指肠切除术或全胃切除术。作者在一个包含30例胃良性肿瘤的个人病例系列中,阐述了5例胃神经起源的良性肿瘤。这些病例均接受了手术切除,其组织学表现为:1例恶性神经鞘瘤、2例神经纤维瘤和2例良性神经鞘瘤。对于恶性神经鞘瘤病例,因复发需要再次干预。尽管进行了手术和化疗,患者仍因腹部和肝脏转移而死亡。

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