Couraud L, Laurent F, Velly J F, Dorcier J, Zanotti L, Martigné C, Drouillard J
Service de Chirurgie Thoracique, Hôpital Xavier Arnozan, Pessac.
Ann Chir. 1990;44(8):649-54.
Computed tomography and magnetic resonance imaging have respectively decreased the incidence of exploratory thoracotomy by 11.6% to 5.7% then 5.3% after their successive inclusion in the assessment of the operability of lung cancers. Based on a systematic comparison of CT and MRI with exploratory thoracotomy in 111 patients, the yield, sensitivity and positive predictive value of these examinations was assessed in relation to tumour extension to various sites: to the chest wall, for which the sensitivity was poor (38% for CT, 54% for MRI) with a moderate predictive value (71% for CT, 77% for MRI); to the mediastinum with improved sensitivity (69% and 72%) but an uncertain predictive value (61% and 72%). The sensitivity and predictive value were then measured for lymph node involvement: N1: moderate sensitivity (69% and 76%) but a good predictive value (95% and 92%); N2 and N3: good sensitivity (79% and 93%) but a poor predictive value (70% and 66%). Apart from a few particular indications specific to MRI, especially in the apex, left hilum and in contact with the atrium, the efficacy of these two investigations is very similar. However, their lack of specificity means that certain exploratory thoracotomies are still justified in order to assess the operability of the tumour. A surgical or mediastinoscopic anatomical assessment is still necessary for a good classification of lymph node extension of lung tumours.
计算机断层扫描(CT)和磁共振成像(MRI)相继被纳入肺癌可切除性评估后,分别使开胸探查术的发生率从11.6%降至5.7%,随后又降至5.3%。基于对111例患者的CT、MRI与开胸探查术的系统比较,评估了这些检查在肿瘤向不同部位扩展方面的检出率、敏感性和阳性预测值:对于胸壁,敏感性较差(CT为38%,MRI为54%),预测价值中等(CT为71%,MRI为77%);对于纵隔,敏感性有所提高(分别为69%和72%),但预测价值不确定(分别为61%和72%)。然后测量了淋巴结受累情况的敏感性和预测价值:N1:敏感性中等(分别为69%和76%),但预测价值良好(分别为95%和92%);N2和N3:敏感性良好(分别为79%和93%),但预测价值较差(分别为70%和66%)。除了MRI特有的一些特殊指征,特别是在肺尖、左肺门以及与心房接触处,这两种检查的效果非常相似。然而,它们缺乏特异性意味着为了评估肿瘤的可切除性,某些开胸探查术仍然是合理的。对于肺癌淋巴结扩展的良好分类,手术或纵隔镜解剖评估仍然是必要的。