Brucher P, Brunier G, Ferrière J M, Le Guillou M
Service d'Urologie, Groupe Hospitalier Pellegrin-Tripode, Bordeaux.
Ann Urol (Paris). 1990;24(6):504-11.
The prognosis of adult renal adenocarcinoma was evaluated by analyzing 322 cases treated by extensive nephrectomy (1979-1988). Five-year actuarial survival curves showed that prognosis was closely correlated with anatomic spread: no clear prognostic significance could be ascribed to venous invasion but involvement of retroperitoneal lymph nodes proved to be nearly as negative a prognostic factor as metastatic disease. The grade of malignancy also had a major impact on prognosis. Because the TNM classification, although accurate, is difficult to use and relies solely on descriptive data, a simple five-stage classification is proposed but remains to be validated. The classification system advocated by Robson groups stages with very different outcomes and consequently seems unhelpful.
通过分析1979年至1988年接受根治性肾切除术治疗的322例病例，评估成人肾腺癌的预后。五年精算生存曲线显示，预后与解剖学扩散密切相关：静脉侵犯无明确的预后意义，但腹膜后淋巴结受累被证明是几乎与转移性疾病同样负面的预后因素。恶性程度分级对预后也有重大影响。由于TNM分类虽然准确，但难以使用且仅依赖描述性数据，因此提出了一种简单的五阶段分类法，但仍有待验证。罗布森（Robson）倡导的分类系统将预后差异很大的阶段归为一组，因此似乎并无帮助。
