血液酒精浓度取决于三氯乙烯和乙醇联合给药的顺序。
[Blood alcohol concentration is dependent on the sequence of the combined administration of trichlorethylene and ethanol].
作者信息
Wolff D L, Weigmann H J
机构信息
Zentralinstitut für Arbeitsmedizin, FB Arbeitstoxikologie, Berlin, DDR.
出版信息
Biomed Biochim Acta. 1990;49(5):421-4.
In equimolar amounts ethanol and trichloroethylene were administered intraperitoneally to male ICR mice in varying sequences. The sequence of administration proved to be decisive for the blood alcohol levels. In relation to ethanol alone following the simultaneous administration of trichloroethylene and ethanol the blood alcohol levels were elevated. This effect is furthermore enhanced if trichloroethylene was administered 1 h prior to ethanol administration. The reversed sequence had no effect on blood alcohol levels.
将等摩尔量的乙醇和三氯乙烯以不同顺序腹腔注射给雄性ICR小鼠。给药顺序被证明对血液酒精水平起决定性作用。与单独给予乙醇相比，在同时给予三氯乙烯和乙醇后，血液酒精水平升高。如果在给予乙醇前1小时给予三氯乙烯，这种效果会进一步增强。相反的顺序对血液酒精水平没有影响。
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