Clinical Testing Center of Chengdu Military, North Tianhui Avenue 270, Chengdu, Sichuan, China.
Cell Biochem Biophys. 2012 Nov;64(2):89-93. doi: 10.1007/s12013-012-9375-9.
The objective of this study was to measure the serum concentrations of C-reactive protein (CRP) in cancer patients and compare with those of immune disease patients and healthy individuals for discriminatory analysis. For this purpose, automatic systems for special protein analysis (Type: Drcon Diognostica Tarbox) was used to measure serum CRP concentrations in 276 cancer patients (Group A), 110 immune disease patients (Group B), 161 phlogistic patients (Group C), and 125 age-matched healthy individuals (Group D). Our data show that serum CRP concentrations in Group A were significantly higher than those in Groups B and D, whereas CRP concentrations in Group B were higher than those in Group D. The differences of serum CRP concentrations between Groups A and B as well as between Groups B and D were significant (P < 0.01). We, therefore, concluded that the measurement of serum CRP concentrations was a fast and accurate method to distinguish between cancer and immune disease patients.
本研究旨在测量癌症患者的血清 C 反应蛋白（CRP）浓度，并与免疫疾病患者和健康个体进行比较，以进行判别分析。为此，使用特殊蛋白质分析自动系统（型号：Drcon Diognostica Tarbox）测量了 276 名癌症患者（A 组）、110 名免疫疾病患者（B 组）、161 名炎症患者（C 组）和 125 名年龄匹配的健康个体（D 组）的血清 CRP 浓度。我们的数据表明，A 组的血清 CRP 浓度明显高于 B 组和 D 组，而 B 组的 CRP 浓度高于 D 组。A 组和 B 组以及 B 组和 D 组之间的血清 CRP 浓度差异均具有统计学意义（P<0.01）。因此，我们得出结论，测量血清 CRP 浓度是区分癌症和免疫疾病患者的一种快速而准确的方法。
