Bland Phillip
Practitioner. 2012 Jan;256(1747):17-20, 2-3.
Epidemiological studies suggest that anxiety and depression are less common in older than younger adults. One in ten people aged > or = 65 fulfils the diagnostic criteria for at least one common mental disorder. Older depressed patients have an increased risk of both cardiac and all-cause mortality. Both anxiety and depression in older patients are often unrecognised and untreated, and have a poor prognosis. There is a progressive decline in the prevalence of common mental disorders above the age of 55. Anxiety and depression often occur together, and share many risk factors. However, anxiety tends to follow threats or traumatic events, whereas depression follows loss events. Chronic diseases, cognitive impairment, pain and functional disability are risk factors for the onset of depression, but not anxiety. Depression is between two and three times more common among those with a chronic physical health problem. Even patients with major depression often remain unrecognised and untreated. Generalised anxiety disorder (GAD) is by far the most common anxiety disorder in older people but most GAD patients are not recognised in primary care and only a third of them receive any form of treatment. Older patients often deny feeling anxious or depressed and are more likely to present with insomnia, irritability, agitation and multiple somatic complaints. GPs may erroneously believe that depression is a normal reaction to the losses of old age, and may be reluctant to initiate treatment. A good case can be made for replacing the PHQ-9 with the 15-item version of the Geriatric Depression Scale which almost entirely avoids somatic questions. This is a screening not a diagnostic tool and does not evaluate symptom severity.
流行病学研究表明,焦虑和抑郁在老年人中比在年轻人中更不常见。每十名65岁及以上的人中就有一人符合至少一种常见精神障碍的诊断标准。老年抑郁症患者的心脏疾病和全因死亡率风险均有所增加。老年患者的焦虑和抑郁往往未被识别和治疗,预后较差。55岁以上人群中常见精神障碍的患病率呈逐渐下降趋势。焦虑和抑郁常同时出现,且有许多共同的风险因素。然而,焦虑往往继发于威胁或创伤性事件,而抑郁则继发于丧失事件。慢性疾病、认知障碍、疼痛和功能残疾是抑郁症发病的风险因素,但不是焦虑症的风险因素。在患有慢性身体健康问题的人群中,抑郁症的发病率是前者的两到三倍。即使是重度抑郁症患者也常常未被识别和治疗。广泛性焦虑障碍(GAD)是老年人中最常见的焦虑障碍,但大多数GAD患者在初级保健中未被识别,只有三分之一的患者接受了任何形式的治疗。老年患者常常否认感到焦虑或抑郁,更有可能表现出失眠、易怒、激动和多种躯体不适症状。全科医生可能错误地认为抑郁是对老年丧失的正常反应,可能不愿开始治疗。用15项老年抑郁量表取代PHQ - 9是有充分理由的,该量表几乎完全避免了躯体问题。这是一种筛查工具而非诊断工具,且不评估症状严重程度。