Department of Obstetrics and Gynecology, University of New Mexico, Albuquerque, NM, USA.
BMC Pregnancy Childbirth. 2012 Jun 21;12:53. doi: 10.1186/1471-2393-12-53.
Preterm birth (PTB) is a substantial health problem that accounts for significant infant morbidity and mortality and poses an economic burden to both individuals and the state of residence. The goal of this study was to identify maternal risk factors for PTB in New Mexico, a poor state with a unique ethnic background, in order to identify populations at increased risk that would benefit from intervention.
This was a cross-sectional retrospective exploratory analysis of 377,770 singleton live births in the state of New Mexico from 1991-2005. Gestational age of less than 37 weeks was defined as PTB. The Kotelchuck Index was used as a measure for level of prenatal care described as inadequate, intermediate, adequate, and intensive.
Of the live births analyzed, 28,036 of these were preterm (7.4%). Overall the PTB rate rose at a rate of 0.18% per year from 1991-2005. Among patients with medical risk factors, the absence of prenatal care was associated with higher odds for PTB as compared to adequate prenatal care. Other risk factors were unmarried status, education less than high school, tobacco/alcohol use, black, Asian, and white Hispanic ethnicity, and the presence of one or more medical risk factors. Statistically significant protective factors for PTB were age 25-29, education surpassing high school, and Native American race.
This study identified several factors that correlate with increased PTB in New Mexico, in particular ethnicity and level of prenatal care. The finding that Native American patients have a lower PTB rate compared to other groups, even though this group is traditionally one of low socioeconomic status in New Mexico, signifies that other factors yet to be identified affect PTB.
早产(PTB)是一个严重的健康问题,导致婴儿发病率和死亡率显著增加,并给个人和居住地州都带来了经济负担。本研究的目的是确定新墨西哥州产妇早产的风险因素,新墨西哥州是一个拥有独特种族背景的贫困州,以便确定处于高风险中的人群,以便对他们进行干预。
这是对 1991-2005 年新墨西哥州 377770 例单胎活产的横断面回顾性探索性分析。胎龄小于 37 周定义为早产。Kotelchuck 指数用于衡量产前护理水平,分为不足、中等、充足和强化。
在所分析的活产儿中,28036 例为早产儿(7.4%)。总体而言,1991-2005 年,PTB 率以每年 0.18%的速度上升。在有医疗风险因素的患者中,与充足的产前护理相比,没有产前护理与更高的早产几率相关。其他风险因素包括未婚、教育程度低于高中、吸烟/饮酒、黑种人、亚洲人和白种西班牙裔,以及存在一个或多个医疗风险因素。PTB 的统计学显著保护因素为 25-29 岁年龄、高中以上教育程度和美洲原住民种族。
本研究确定了与新墨西哥州早产相关的几个因素,特别是种族和产前护理水平。尽管美洲原住民患者的社会经济地位通常较低,但与其他群体相比,他们的早产率较低,这表明还有其他尚未确定的因素影响早产。