Nelson D A
Department of Pathology, State University of New York Health Science Center, Syracuse.
Clin Lab Med. 1990 Dec;10(4):649-59.
The myelopoietic system includes the hematopoietic cells derived from a common hematopoietic stem cell that includes erythroid, granulocytic, monocytic, and megakaryocytic lineages. The contributions of molecular genetic techniques to hematopoiesis in the past 5 years have led to quantum leaps in our understanding, but there is room for further research. Current concepts of stem cells and the hematopoietic microenvironment are discussed, as are committed progenitor cells and hematopoietic growth factors, particularly those concerning the neutrophilic, monocytic, and erythroid systems.
骨髓造血系统包括源自共同造血干细胞的造血细胞,这些造血细胞包括红系、粒系、单核系和巨核系谱系。在过去5年中,分子遗传学技术对造血作用的研究使我们的认识有了巨大飞跃,但仍有进一步研究的空间。本文讨论了干细胞和造血微环境的当前概念,以及定向祖细胞和造血生长因子,特别是与中性粒细胞、单核细胞和红系系统有关的因子。