Caflisch C R, DuBose T D
Department of Internal Medicine, University of Texas Medical Branch, Galveston 77550.
Contraception. 1990 Nov;42(5):589-95. doi: 10.1016/0010-7824(90)90085-a.
The effect of bilateral vasectomy on in situ pH in seminiferous tubules, initial segments, proximal caput, middle corpus and proximal cauda epididymides of the rat has been studied employing in vivo microelectrode techniques. After bilateral vasectomy of four weeks duration, a significant increase in acidity of luminal fluid in the initial segments of the caput epididymides was observed. By eight weeks post vasectomy, luminal pH in the initial segments was significantly more acid as compared to sham-operated control animals or four weeks vasectomy while, in contrast, luminal pH in the proximal cauda epididymides was significantly more alkaline. The alteration of luminal fluid pH in the initial segments and proximal cauda epididymides after bilateral vasectomy may be the result of impairment of acid-base, as well as water transport pathways.
采用体内微电极技术，研究了双侧输精管结扎对大鼠生精小管、起始段、附睾头近端、附睾体中部及附睾尾近端原位pH值的影响。在进行为期四周的双侧输精管结扎后，观察到附睾头起始段管腔液酸度显著增加。输精管结扎术后八周，与假手术对照组动物或输精管结扎四周的动物相比，起始段的管腔pH值显著更酸，而相比之下，附睾尾近端的管腔pH值则显著更碱。双侧输精管结扎后，附睾起始段和附睾尾近端管腔液pH值的改变可能是酸碱及水转运途径受损的结果。
