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《纳库鲁后部眼病研究:肯尼亚纳库鲁的盲与视力损伤的患病率和方法》。

The Nakuru posterior segment eye disease study: methods and prevalence of blindness and visual impairment in Nakuru, Kenya.

机构信息

International Centre for Eye Health, Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK.

出版信息

Ophthalmology. 2012 Oct;119(10):2033-9. doi: 10.1016/j.ophtha.2012.04.019. Epub 2012 Jun 19.

Abstract

OBJECTIVES

To estimate the prevalence of blindness and visual impairment (VI) in adults aged ≥50 years in the Nakuru district of Kenya and to identify sociodemographic risk factors for these conditions. We also sought to validate the Rapid Assessment of Avoidable Blindness (RAAB) methodology.

PARTICIPANTS

There were 5010 subjects enumerated for this study. Of these, 4414 participants underwent examination, for a response rate of 88.1%.

DESIGN

Cross-sectional, population-based survey.

METHODS

Cluster random samplings with probability proportionate to size procedures were used to select a representative cross-sectional sample of adults aged ≥50 years. Each participant was interviewed, had distance visual acuity (VA) measured with reduced logarithm of the minimal angle of resolution tumbling-E chart, underwent autorefraction, and thereby had measurements of presenting, uncorrected, and best-corrected VA. All participants, regardless of vision, underwent detailed ophthalmic examinations including slit-lamp assessment and dilated retinal photographs.

MAIN OUTCOME MEASURES

Visual acuity of <6/12.

RESULTS

A representative sample of 4414 adults were enumerated (response rate, 88.1%). The prevalence of blindness (VA < 3/60 in better eye) was 1.6% (95% confidence interval [CI], 1.2-2.1%) and of VI, 0.4% (95% CI, 0.3-0.7%); 8.1% (95% CI, 7.2-9.2%); and 5.1% (95% CI, 4.3-6.1%) were severely (<6/60-3/60), moderately (<6/18-6/60), or mildly (<6/12-6/18) visually impaired, respectively. Being male, having less education, having Kalenjin tribal origin, and being ≥80 years old were associated with increased blindness prevalence. Prevalence estimates were comparable to a RAAB performed in the same area 2 years earlier.

CONCLUSIONS

This survey provides reliable estimates of blindness and VI prevalence in Nakuru. Older age and tribal origin were identified as predictors of these conditions. This survey validates the use of RAAB as a method of estimating blindness and VI prevalence.

摘要

目的

估计肯尼亚纳库鲁地区 50 岁及以上成年人的盲症和视力损伤(VI)的患病率,并确定这些疾病的社会人口学风险因素。我们还试图验证快速评估可避免盲症(RAAB)方法。

参与者

这项研究共登记了 5010 人。其中,4414 名参与者接受了检查,应答率为 88.1%。

设计

横断面、基于人群的调查。

方法

采用集群随机抽样,概率与大小成正比,以选择代表性的 50 岁及以上成年人的横断面样本。对每位参与者进行访谈,使用简化最小角分辨率翻转 E 图表测量远距离视力(VA),进行自动折射,从而测量当前、未经矫正和最佳矫正的 VA。所有参与者,无论视力如何,均接受详细的眼科检查,包括裂隙灯检查和散瞳眼底照相。

主要观察指标

视力<6/12。

结果

共登记了 4414 名成年人的代表性样本(应答率为 88.1%)。盲症(较好眼视力<3/60)的患病率为 1.6%(95%置信区间[CI],1.2-2.1%),视力损伤的患病率为 0.4%(95%CI,0.3-0.7%);8.1%(95%CI,7.2-9.2%)和 5.1%(95%CI,4.3-6.1%)分别为严重(<6/60-3/60)、中度(<6/18-6/60)和轻度(<6/12-6/18)视力损伤。男性、受教育程度较低、属于卡伦金部落和年龄≥80 岁与盲症患病率增加相关。患病率估计与 2 年前在同一地区进行的 RAAB 结果相当。

结论

本调查提供了纳库鲁地区盲症和 VI 患病率的可靠估计。年龄较大和部落出身被确定为这些疾病的预测因素。本调查验证了 RAAB 作为估计盲症和 VI 患病率的方法的有效性。

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