• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

对来自地中海青铜时代的 3000 年前木乃伊脑组织的古神经组织学研究。

A paleoneurohistological study of 3,000-year-old mummified brain tissue from the mediterranean bronze age.

机构信息

Department of Prehistory, Ancient History and Archaeology, Hospital Clínic and Institut d'Investigacions August Pi i Sunyer, University of Barcelona, Barcelona, Spain.

出版信息

Pathobiology. 2012;79(5):239-46. doi: 10.1159/000334353. Epub 2012 Jun 21.

DOI:10.1159/000334353
PMID:22722563
Abstract

OBJECTIVES

Mummified nervous tissue is very rarely found in ancient remains and usually corresponds to corpses which were frozen or preserved in bogs, conditions which limit tissue autolysis and bacterial degradation. Here, we show the unusual finding of spontaneously mummified brain tissue from several individuals from the little known megalithic talaiotic culture of the island of Minorca, dating approximately 3,000 years before present and corresponding to the late Mediterranean Bronze Age.

METHODS

These individuals were part of an intact burial site containing 66 subjects. Intracraneal samples were carefully rehydrated with Sandison's solution. We used classical histochemical as well as 2D and 3D (scanning) electron-microscopic techniques.

RESULTS

We provide evidence of the nervous nature of the samples as well as a detailed description of the morphological features of these ancient tissues. The intracranial material consisted of well-preserved eosinophilic reticular tissue and, although mostly absent, some exceptional pigment-containing neurons were identified.

CONCLUSIONS

We present a detailed morphological analysis which can provide valuable information and guidelines for the interpretation of this scarce type of mummified samples and provide explanations for this surprising preservation.

摘要

目的

木乃伊化的神经组织在古代遗骸中非常罕见,通常与那些被冷冻或保存在沼泽中的尸体相对应,这些条件限制了组织自溶和细菌降解。在这里,我们展示了来自马略卡岛的鲜为人知的巨石塔利奥文化的几个个体的自发木乃伊化脑组织的异常发现,这些个体的年代约为现在 3000 年前,对应于地中海青铜时代晚期。

方法

这些个体是一个完整的埋葬地点的一部分,其中包含 66 个个体。颅内样本用桑迪森溶液小心地再水化。我们使用了经典的组织化学以及 2D 和 3D(扫描)电子显微镜技术。

结果

我们提供了证据表明这些样本具有神经性质,并详细描述了这些古代组织的形态特征。颅内材料由保存完好的嗜酸性网状组织组成,虽然大部分缺失,但也鉴定出了一些罕见的含色素神经元。

结论

我们进行了详细的形态学分析,这可以为这种罕见类型的木乃伊化样本的解释提供有价值的信息和指导,并为这种令人惊讶的保存提供解释。

相似文献

1
A paleoneurohistological study of 3,000-year-old mummified brain tissue from the mediterranean bronze age.对来自地中海青铜时代的 3000 年前木乃伊脑组织的古神经组织学研究。
Pathobiology. 2012;79(5):239-46. doi: 10.1159/000334353. Epub 2012 Jun 21.
2
Soft tissue tumors in palaeopathology: a review.古病理学中的软组织肿瘤:综述。
Pathobiology. 2012;79(5):257-67. doi: 10.1159/000337292. Epub 2012 Jun 21.
3
Paleopathology in South American mummies: a review and new findings.南美的木乃伊中的古病理学:综述和新发现。
Pathobiology. 2012;79(5):247-56. doi: 10.1159/000334087. Epub 2012 Jun 21.
4
Palaeopathology: the study of disease in the past.古病理学:对过去疾病的研究。
Pathobiology. 2012;79(5):221-7. doi: 10.1159/000335165. Epub 2012 Jun 21.
5
The neuropathology of South American mummies.南美木乃伊的神经病理学
Neurosurgery. 1995 Apr;36(4):756-61. doi: 10.1227/00006123-199504000-00017.
6
A Systematic Approach to the Application of Soft Tissue Histopathology in Paleopathology.古病理学中软组织组织病理学应用的系统方法
Biomed Res Int. 2015;2015:631465. doi: 10.1155/2015/631465. Epub 2015 Aug 6.
7
[Preservation of cutaneous structures of egyptian mummies. An ultrastructural study].[埃及木乃伊皮肤结构的保存。一项超微结构研究]
Ann Dermatol Venereol. 1994;121(6-7):470-5.
8
Morphologic-anthropological investigations in tomb K93.12 at Dra' Abu el-Naga (Western Thebes, Egypt).在埃及西部底比斯德拉阿布埃尔纳加的K93.12号墓进行的形态学-人类学调查。
Anthropol Anz. 2014;71(1-2):105-22. doi: 10.1127/0003-5548/2014/0401.
9
Histological analysis and staining techniques modified and verified on ancient mummified tissues to study microorganism infestations.对古代木乃伊组织进行改良和验证的组织学分析及染色技术,以研究微生物感染情况。
Boll Soc Ital Biol Sper. 1999 Jul-Aug;75(7-8):39-45.
10
Immunohistochemistry: a new outlook in histopaleopathology.免疫组织化学:组织古病理学的新视角。
Boll Soc Ital Biol Sper. 1995 Mar-Apr;71(3-4):105-10.

引用本文的文献

1
A novel integrated extraction protocol for multi-omic studies in heavily degraded samples.一种新型的综合提取方案,用于对严重降解样本进行多组学研究。
Sci Rep. 2024 Jul 30;14(1):17477. doi: 10.1038/s41598-024-67104-8.
2
Human brains preserve in diverse environments for at least 12 000 years.人类大脑在各种环境中至少保存了 12000 年。
Proc Biol Sci. 2024 Mar 27;291(2019):20232606. doi: 10.1098/rspb.2023.2606. Epub 2024 Mar 20.
3
Papaver somniferum in seventeenth century (Italy): archaeotoxicological study on brain and bone samples in patients from a hospital in Milan.
十七世纪(意大利)的罂粟:米兰一家医院的脑和骨样本的考古毒理学研究。
Sci Rep. 2023 Feb 28;13(1):3390. doi: 10.1038/s41598-023-27953-1.