Division of Interventional Neuroradiology, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA.
AJNR Am J Neuroradiol. 2012 Nov;33(10):1875-81. doi: 10.3174/ajnr.A3111. Epub 2012 Jun 21.
While spinal DSA remains the reference standard technique for spinovascular imaging, visualizing spinal veins remains challenging due to their small size and motion artifacts. This study evaluates the ability of FPCA to overcome these obstacles.
Sixty-three FPCAs, performed by intersegmental artery injections in 57 patients, were prospectively evaluated. Entrance skin doses were compared with standard spinal DSA runs, including a venous phase and cerebral FPCAs. FPCA contributions were stratified as 1) provided no added information, 2) complemented spinal DSA findings, 3) assisted therapy planning, and 4) contributed principal diagnostic findings.
No complications were observed. Diagnoses included vascular malformations (44%), stroke (9%), venous anomalies (10%), other (9%), and unremarkable (28%). Mean entrance skin doses were of 419 mGy for FPCA, 161 mGy for spinal DSA with venous phase, and 309 mGy for cerebral FPCAs. FPCA contributed the principal diagnostic finding in 16 cases (25.4%), assisted therapy planning in 13 cases (20.6%), complemented spinal DSA findings in 12 cases (19.1%), and provided no additional information in 20 cases (31.7%). In 8 of these 20 cases, FPCA documented a spinal venous anatomy that was poorly visualized or not visualized on spinal DSA.
Spinal FPCA is safe, with a moderate increase in radiation dose, compared with spinal DSA with venous phase or cerebral FPCA. It proved particularly valuable for therapy planning and the diagnosis of venous abnormalities. This study suggests that FPCA has an important role to play in the evaluation of the spinal venous system.
虽然脊髓 DSA 仍然是血管成像的参考标准技术,但由于脊髓静脉的体积小和运动伪影,对其进行可视化仍然具有挑战性。本研究评估了 FPCA 克服这些障碍的能力。
前瞻性评估了 57 名患者 63 次通过节段间动脉注射进行的 FPCA。比较了入口皮肤剂量与标准脊髓 DSA 运行,包括静脉期和脑 FPCA。FPCA 的贡献分为 1)未提供附加信息,2)补充脊髓 DSA 发现,3)辅助治疗计划,4)提供主要诊断发现。
未观察到并发症。诊断包括血管畸形(44%)、中风(9%)、静脉异常(10%)、其他(9%)和无明显异常(28%)。FPCA 的平均入口皮肤剂量为 419mGy,脊髓 DSA 静脉期为 161mGy,脑 FPCA 为 309mGy。FPCA 在 16 例(25.4%)中提供了主要诊断发现,在 13 例(20.6%)中辅助治疗计划,在 12 例(19.1%)中补充脊髓 DSA 发现,在 20 例(31.7%)中未提供附加信息。在这 20 例中的 8 例中,FPCA 记录了脊髓 DSA 显示不佳或未显示的脊髓静脉解剖结构。
与脊髓 DSA 静脉期或脑 FPCA 相比,脊髓 FPCA 安全,辐射剂量适度增加。它在治疗计划和静脉异常的诊断方面特别有价值。本研究表明,FPCA 在评估脊髓静脉系统方面具有重要作用。