Lell Michael M, Ditt Hendrik, Panknin Christoph, Sayre James W, Klotz Ernst, Ruehm Stefan G, Villablanca J Pablo
Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Invest Radiol. 2008 Jan;43(1):27-32. doi: 10.1097/RLI.0b013e31815597ac.
Bone subtraction techniques have been shown to enhance cranial computed tomography angiography (CTA). The aims of this study were to assess the feasibility of bone subtraction CTA (BSCTA) in cervical CTA, test whether a late venous CT (LVCT) scan can be used as bone mask instead of a low-dose nonenhanced CT (NECT), and to evaluate the impact of patient motion on image quality.
Thirty-six patients underwent BSCTA for the evaluation of the neck vessels with a 64-slice CT system using commercially available software. Eighteen patients had a low-dose NECT scan before CTA, and 18 patients had an LVCT scan after CTA. Subtraction quality for vascular segments was evaluated independently by 2 examiners. Cohen's Kappa was applied to evaluate interobserver reliability, and Wilcoxon signed rank test was used to test for differences between the 2 groups. Motion between the 2 scans was measured and correlated to image quality.
BSCTA using both NECT and LVCT scans as masks was successfully applied in all patients. Image quality did not differ significantly between the 2 groups, and interobserver agreement was high (k 0.5-1). Motion between the scans was highest for the jaw and hyoid, and lowest for the upper and lower spine. Decreased image quality on the subtracted images was associated with increased motion for the external carotid and vertebral artery, independent of mask type (P = 0.002-0.04).
BSCTA techniques can be successfully applied in the neck. If parenchymal phase imaging is indicated, the LVCT can be used as a bone subtraction mask and diagnostic scan, eg, for tumor imaging.
骨减影技术已被证明可增强头颅计算机断层血管造影(CTA)。本研究的目的是评估骨减影CTA(BSCTA)在颈部CTA中的可行性,测试延迟静脉CT(LVCT)扫描是否可作为骨掩模替代低剂量非增强CT(NECT),并评估患者运动对图像质量的影响。
36例患者使用商用软件通过64层CT系统接受BSCTA检查以评估颈部血管。18例患者在CTA前进行了低剂量NECT扫描,18例患者在CTA后进行了LVCT扫描。两名检查者独立评估血管段的减影质量。采用Cohen's Kappa评估观察者间的可靠性,采用Wilcoxon符号秩检验测试两组之间的差异。测量两次扫描之间的运动并将其与图像质量相关联。
以NECT和LVCT扫描作为掩模的BSCTA在所有患者中均成功应用。两组之间的图像质量无显著差异,观察者间一致性较高(κ=0.5 - 1)。扫描之间的运动在颌骨和舌骨处最高,在上、下脊柱处最低。减影图像上图像质量的下降与颈外动脉和椎动脉运动的增加相关,与掩模类型无关(P = 0.002 - 0.04)。
BSCTA技术可成功应用于颈部。如果需要实质期成像,LVCT可作为骨减影掩模和诊断扫描,例如用于肿瘤成像。