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The parental origin of de novo X-autosome translocations in females with Duchenne muscular dystrophy revealed by M27 beta methylation analysis.

作者信息

Robinson D O, Boyd Y, Cockburn D, Collinson M N, Craig I, Jacobs P A

机构信息

Wessex Regional Genetics Laboratory, General Hospital, Salisbury.

出版信息

Genet Res. 1990 Oct-Dec;56(2-3):135-40. doi: 10.1017/s0016672300035217.

DOI:10.1017/s0016672300035217
PMID:2272503
Abstract

The parental origin of 3 de novo X-autosome translocations in females with Duchenne Muscular Dystrophy (DMD) was studied by means of methylation analysis using the X-linked probe M27 beta. In all three the translocation was found to be paternal in origin. The parental origin of X-autosome translocations in females with and without DMD is compared with other structural abnormalities of the X and with autosomal translocations.

摘要

相似文献

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The parental origin of de novo X-autosome translocations in females with Duchenne muscular dystrophy revealed by M27 beta methylation analysis.
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