Department of Medical Biochemistry, Etlik Zubeyde Hanim Obstetrics and Gynecology Training and Research Hospital, Ankara, Turkey.
Acupunct Med. 2012 Sep;30(3):203-7. doi: 10.1136/acupmed-2012-010127. Epub 2012 Jun 22.
Obesity is an energy balance problem caused by overeating. Obesity treatment includes diet, exercise, behaviour treatment, pharmacotherapy and surgery; in addition, acupuncture is also an option.
To investigate the effect of acupuncture on weight loss and whether a brief acupuncture treatment of 5 weeks can change circulating levels of leptin, ghrelin, insulin and cholecystokinin (CCK) in obese women.
40 women with a body mass index (BMI)>30 kg/m(2) were equally randomised to either an acupuncture group or a sham (non-penetrating) acupuncture group and received treatment at LI4, HT7, ST36, ST44 and SP6 bilaterally. Both groups had two sessions of 20 min/week for a total of 10 sessions. Serum insulin, leptin, plasma ghrelin and CCK levels were measured by ELISA.
Acupuncture treatment decreased insulin and leptin levels and induced weight loss, together with a decrease in BMI compared with sham acupuncture. Furthermore, between-group analyses demonstrated increases in plasma ghrelin and CCK levels in subjects who received acupuncture treatment.
These findings suggest that acupuncture may help to regulate weight owing to its beneficial effects on hormones such as insulin, leptin, ghrelin and CCK in obese subjects even after a few weeks of treatment.
肥胖是一种由过度饮食引起的能量平衡问题。肥胖的治疗包括饮食、运动、行为治疗、药物治疗和手术；此外，针灸也是一种选择。
探讨针灸对减肥的影响，以及 5 周的短暂针灸治疗是否能改变肥胖女性循环中的瘦素、胃饥饿素、胰岛素和胆囊收缩素（CCK）水平。
40 名体重指数（BMI）>30kg/m²的女性被平均随机分为针灸组和假（非穿透）针灸组，分别接受双侧 LI4、HT7、ST36、ST44 和 SP6 的治疗。两组均每周进行 2 次 20 分钟的治疗，共 10 次。通过 ELISA 测量血清胰岛素、瘦素、血浆胃饥饿素和 CCK 水平。
与假针灸相比，针灸治疗降低了胰岛素和瘦素水平，诱导体重减轻，同时降低了 BMI。此外，组间分析显示，接受针灸治疗的受试者血浆胃饥饿素和 CCK 水平升高。
这些发现表明，即使在几周的治疗后，针灸可能通过对胰岛素、瘦素、胃饥饿素和 CCK 等激素的有益作用，有助于调节肥胖患者的体重。
