Loeuille Damien
Service de rhumatologie, hôpital Brabois, CHU de Nancy 54500 Vandeuvre-lès-Nancy.
Rev Prat. 2012 May;62(5):625-9.
Radiograph is the gold standard to establish the diagnosis of osteoarthritis (OA) and to classify patients in function structural severity according to Kellgren and Lawrence's classification. Radiograph should be performed on standing position for weight-bearing joints. In clinical practice, MRI is usually used to eliminate other diagnosis when X-rays are considered as normal and to precise abarticular structures and bone lesions affected in OA. This imaging technic allows to directly visualize articular cartilage damage with an excellent correlation compared to arthroscopy But MRI is also able to depict articular damages associated with OA such as bone marrow lesion (BML), osteophytes, cysts, joint effusion, synovitis, menisci lesions, tendinitis and bursitis. Some of them were associated with pain (BML, synovitis, effusion) while some articular lesions were more implicated in chondrolysis (focal cartilage lesion, BML, menisci lesion, synovitis effusion). In cases of X-ray abnormalities (osteophytes, joint space narrowing, bone condensation, cysts), menisci lesions should not be considered as responsible for pain in knee OA. Thus, MRI is the only imaging technic able to precise which articular structure is affected during the disease (bone, synovial tissue or abarticular tissues) and helps clinician to have a more targeted therapeutic approach.
X线片是诊断骨关节炎(OA)以及根据凯尔格伦和劳伦斯分类法对患者进行功能结构严重程度分级的金标准。对于负重关节,应在站立位进行X线片检查。在临床实践中,当X线片显示正常时,通常使用MRI来排除其他诊断,并精确显示OA中受影响的关节外结构和骨病变。与关节镜检查相比,这种成像技术能够直接观察到关节软骨损伤,且二者具有极佳的相关性。但是,MRI也能够显示与OA相关的关节损伤,如骨髓病变(BML)、骨赘、囊肿、关节积液、滑膜炎、半月板损伤、肌腱炎和滑囊炎。其中一些与疼痛有关(BML、滑膜炎、积液),而一些关节损伤与软骨溶解关系更为密切(局灶性软骨损伤、BML、半月板损伤、滑膜炎积液)。在X线片有异常(骨赘、关节间隙变窄、骨质硬化、囊肿)的情况下,半月板损伤不应被视为膝关节OA疼痛的原因。因此,MRI是唯一能够精确显示疾病过程中哪些关节结构受到影响(骨骼、滑膜组织或关节外组织)的成像技术,并有助于临床医生采取更有针对性的治疗方法。