Department of Surgery, New Jersey Medical School - UMDNJ, 140 Bergen Street, Suite E1620, Newark, NJ 07103, USA.
Clin Plast Surg. 2012 Jul;39(3):311-24. doi: 10.1016/j.cps.2012.05.002. Epub 2012 Jun 2.
Negative pressure wound therapy (NPWT) has overwhelmed the wound-healing world. A systematic review puts it into perspective. The authors have developed an algorithm after careful evaluation and analysis of the scientific literature supporting the use of these devices. This article describes mechanisms of action, technical considerations, wound preparation, and clinical evidence, reviews the literature, and discusses NPWT use in specific wounds, such as diabetic foot ulcers, open abdomen, pressure ulcers, open fractures, sterna wounds, grafts, and flaps. Contraindications for and complications of NPWT are outlined, and specific recommendations given for the situations in which the authors use NPWT.
负压伤口治疗（NPWT）已经席卷了整个伤口愈合领域。一项系统评价对其进行了透视分析。作者在仔细评估和分析了支持这些设备使用的科学文献后，制定了一个算法。本文描述了作用机制、技术考虑因素、伤口准备和临床证据，回顾了文献，并讨论了 NPWT 在特定伤口中的应用，如糖尿病足溃疡、开放性腹部、压疮、开放性骨折、胸骨伤口、移植物和皮瓣。概述了 NPWT 的禁忌证和并发症，并给出了作者使用 NPWT 的具体情况的建议。
