Emergency Department, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Curr Opin Crit Care. 2012 Aug;18(4):308-17. doi: 10.1097/MCC.0b013e3283557a63.
This article aims to make a review of the up-to-date knowledge on anaphylaxis and outline the recent advances on pathophysiology, diagnosis, and management of anaphylaxis.
New data confirm the increase in prevalence of anaphylaxis and emphasize immunopathologic mechanisms. However, anaphylaxis is often underdiagnosed and guidelines are poorly applied, particularly in emergency departments.
An improvement of rapid diagnosis and treatment combined with education of population will decrease mortality and morbidity of anaphylaxis.
本文旨在综述过敏反应的最新知识,概述过敏反应的病理生理学、诊断和管理的最新进展。
新数据证实过敏反应的患病率增加,并强调了免疫病理机制。然而,过敏反应常常被漏诊,指南的应用也很差,特别是在急诊科。
快速诊断和治疗的改善结合人群教育将降低过敏反应的死亡率和发病率。